Monacolin J

Monacolin J is a statin made by red yeast rice. Monacolin J is a precursor to simvastatin and has potential neuroprotective activities.[1]

Monacolin J
Names
IUPAC name
(4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-8-Hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]-4-hydroxyoxan-2-one
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.110.662
UNII
Properties
C19H28O4
Molar mass 320.429 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. "Semisynthesis of novel monacolin J derivatives: hypocholesterolemic and neuroprotective activities". J. Antibiot. 63 (8): 499–505. August 2010. doi:10.1038/ja.2010.76. PMID 20648024.


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