Michael J. Sofia

Michael J. Sofia is a chemist whose main research focus is hepatitis C virus and hepatitis B virus drug discovery. He was a co-recipient of the Lasker-DeBakey Clinical Medical Research Award for his work on hepatitis C in 2016[1] and of the Gertrude B. Elion Memorial Award from the International Society for Antiviral Research in 2017.[2]

Michael J. Sofia
Alma mater
Scientific career
Institutions
External video
“Acceptance Remarks, 2016 Lasker Awards Ceremony”, Lasker Foundation, 2016.

Career

Sofia earned a bachelor's degree in chemistry from Cornell University, and Ph.D. in organic chemistry from the University of Illinois Urbana-Champaign.[3] He did a postdoctoral fellow at Columbia University, followed by work as a research scientist at biotech companies including the Squibb Institute for Medical Research. Eli Lilly and Company, and Bristol-Myers Squibb.[4] He was Senior Vice President of Chemistry at Pharmasset from 2005 to 2012 when Pharmasset was acquired by Gilead, after which he became a senior advisor.

Michael J. Sofia is currently the Chief Scientific Officer and co-founder of Arbutus Biopharma, formerly as OnCore Biopharma prior to its 2015 merger with Tekmira Pharmaceuticals.[5]

Awards

Michael J. Sofia was awarded the 2016 Lasker-DeBakey Clinical Medical Research Award for his research on hepatitis C, along with Charles M. Rice and Ralf F. W. Bartenschlager.[1] He was also awarded the 2016 IUPAC-Richter Prize in Medicinal Chemistry[6] and the Economist's 2015 Innovation Award in the Bioscience category for the development of sofosbuvir, which was named after Sofia for his contributions to the discovery and development of the drug.[7] He received the Gertrude B. Elion Memorial Award of the International Society for Antiviral Research (2017).[2]:11

References
  1. "Hepatitis C replicon system and drug development - The Lasker Foundation". The Lasker Foundation.
  2. Vere Hodge, R. Anthony, ed. (2019). The International Society for Antiviral Research: The Third Decade 2008-2017 (PDF). International Society for Antiviral Research.
  3. "Sofia, Michael". American Chemical Society. Retrieved 13 May 2020.
  4. Palese, Peter (6 December 2016). "Profile of Charles M. Rice, Ralf F. W. Bartenschlager, and Michael J. Sofia, 2016 Lasker–DeBakey Clinical Medical Research Awardees". Proceedings of the National Academy of Sciences. pp. 13934–13937. doi:10.1073/pnas.1616592113. Retrieved 13 May 2020.
  5. "Tekmira Pharmaceuticals and OnCore Biopharma Announce Merger Agreement to Create Leading Global Hepatitis B Virus Company". www.sec.gov.
  6. "Michael J. Sofia, Ph.D. is Awarded the 2016 IUPAC-Richter Prize - IUPAC - International Union of Pure and Applied Chemistry". IUPAC. 2 March 2016.
  7. Gounder, Celine (December 9, 2013). "A Better Treatment for Hepatitis C". The New Yorker.
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