Methylhippuric acid

Methylhippuric acid is a carboxylic acid and organic compound. Methylhippuric acid has three isomers. The isomers include 2-, 3-, and 4-methylhippuric acid.[1]

Methylhippuric acid

Chemical structures of 2-, 3-, and 4-methylhippuric acid
Names
Other names
Toluric acid; N-(Toluoyl)glycine
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
EC Number
  • 2-: 255-622-7
  • 4-: 248-231-8
UNII
Properties
C10H11NO3
Molar mass 193.202 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Methylhippuric acids are metabolites of the isomers of xylene.[1][2] The presence of methylhippuric acid can be used as a biomarker to determine exposure to xylene.[2][3]

See also

References

  1. "HIPPURIC and METHYL HIPPURIC ACIDS in urine" (PDF). NIOSH Manual of Analytical Methods (NMAM) (Fourth ed.).
  2. Inoue, O.; Seiji, K.; Kawai, T.; Watanabe, T.; Jin, C.; Cai, S. X.; Chen, Z.; Qu, Q. S.; Zhang, T.; Ikeda, M. (1993). "Excretion of methylhippuric acids in urine of workers exposed to a xylene mixture: Comparison among three xylene isomers and toluene". International Archives of Occupational and Environmental Health. 64 (7): 533–9. doi:10.1007/bf00381104. PMID 8482596.
  3. Kira S (1977). "Measurement by gas chromatography of urinary hippuric acid and methylhippuric acid as indices of toluene and xylene exposure". Occupational and Environmental Medicine. 34 (305–309): 305–309. doi:10.1136/oem.34.4.305. PMC 1008281. PMID 588486.
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