Medronic acid

Medronic acid
Names
	IUPAC name methanediylbis(phosphonic acid)
	Other names methanediphosphonic acid; methylenebis(phosphonic acid); methylene diphosphonate; medronate; phosphonomethylphosphonic acid; MDP
Identifiers
CAS Number	1984-15-2 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:43945 ;
ChEMBL	ChEMBL180570 ;
ChemSpider	15308 ;
ECHA InfoCard	100.016.229
KEGG	D04887 ;
PubChem CID	16124;
UNII	73OS0QIN3O ;
CompTox Dashboard (EPA)	DTXSID8045696 ;
	InChI InChI=1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7) Key: MBKDYNNUVRNNRF-UHFFFAOYSA-N ;
	SMILES O=P(O)(O)CP(=O)(O)O;
Properties
Chemical formula	CH6O6P2
Molar mass	176.001 g·mol−1
Melting point	199 to 200 °C (390 to 392 °F; 472 to 473 K)[1]
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	45-50 mg/kg (i.v., mice, rabbits)[1]
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Medronic acid (conjugate base, medronate), also known as methylene diphosphonate, is the smallest bisphosphonate. Its complex with radioactive technetium, ^99mTc medronic acid, is used in nuclear medicine to detect bone abnormalities, including metastases.

References

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