Maneb

{{Chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 434399765 | ImageFile = Maneb.svg | ImageAlt = | IUPACName = [[2-[(Dithiocarboxy)amino]ethyl]carbamodithioato]](2-)-kS,kS']manganese | OtherNames = Manganese ethylene-1,2-bisdithiocarbamate, polymer |Section1=!Identifiers |-

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CAS Number

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12427-38-2^Y

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3D model (JSmol)

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Interactive image

|- | ChemSpider

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none

|- | ECHA InfoCard | 100.032.400 |- | MeSH | Maneb |-

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PubChem CID

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3032581

|- | UNII

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K221E12G7T^Y

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CompTox Dashboard (EPA)

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DTXSID9020794

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InChI

InChI=1S/C4H8N2S4.Mn/c7-3(8)5-1-2-6-4(9)10;/h1-2H2,(H2,5,7,8)(H2,6,9,10);/q;+2/p-2
Key: YKSNLCVSTHTHJA-UHFFFAOYSA-L

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SMILES

[Mn+]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)[S-]

|- |Section2=!Properties |-

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Chemical formula

| (C₄H₆MnN₂S₄)_n |- | Appearance | Yellow to brown colored crystalline solid |- | Density | 1.92 g/cm³ |- | Melting point | 192 to 204 °C (378 to 399 °F; 465 to 477 K) (decomposes) |-

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Solubility in water

| 160 mg/L |- |Section3= }}

Maneb is a fungicide and a polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand.[1]

Applications

It can be also used to create a toxin-based animal model of Parkinson's disease, usually in primates.[2]

Regulation

It was included in a pesticide ban proposed by the Swedish Chemicals Agency [3] and approved by the European Parliament on January 13, 2009.[4]

References

Arno H. Reidies "Manganese Compounds" Ullmann's Encyclopedia of Chemical Technology 2007; Wiley-VCH, Weinheim. doi:10.1002/14356007.a16_123
Cicchetti F, Drouin-Ouellet J, Gross RE (September 2009). "Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?". Trends Pharmacol. Sci. 30 (9): 475–83. doi:10.1016/j.tips.2009.06.005. PMID 19729209.
"Interpretation of criteria for approval of active substances in the proposed EU plant protection regulation". Swedish Chemicals Agency (KemI). 2008-09-23. Archived from the original on 2009-01-01. Retrieved 2009-01-14.
"MEPs approve pesticides legislation". 2009-01-13. Archived from the original on 2009-01-25. Retrieved 2009-01-14.

External links

Maneb in the Pesticide Properties DataBase (PPDB)

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[Reidies-1] Arno H. Reidies "Manganese Compounds" Ullmann's Encyclopedia of Chemical Technology 2007; Wiley-VCH, Weinheim. doi:10.1002/14356007.a16_123

[pmid19729209-2] Cicchetti F, Drouin-Ouellet J, Gross RE (September 2009). "Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?". Trends Pharmacol. Sci. 30 (9): 475–83. doi:10.1016/j.tips.2009.06.005. PMID 19729209.

[3] "Interpretation of criteria for approval of active substances in the proposed EU plant protection regulation". Swedish Chemicals Agency (KemI). 2008-09-23. Archived from the original on 2009-01-01. Retrieved 2009-01-14.

[4] "MEPs approve pesticides legislation". 2009-01-13. Archived from the original on 2009-01-25. Retrieved 2009-01-14.