MAN1B1

Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase is an enzyme that in humans is encoded by the MAN1B1 gene.[5][6][7]

MAN1B1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMAN1B1, ERMAN1, MANA-ER, MRT15, ERManI, mannosidase alpha class 1B member 1
External IDsOMIM: 604346 MGI: 2684954 HomoloGene: 5230 GeneCards: MAN1B1
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9q34.3Start137,086,985 bp[1]
End137,109,183 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

11253

227619

Ensembl

ENSG00000177239

ENSMUSG00000036646

UniProt

Q9UKM7

A2AJ15

RefSeq (mRNA)

NM_016219

NM_001029983

RefSeq (protein)

NP_057303

NP_001025154

Location (UCSC)Chr 9: 137.09 – 137.11 MbChr 2: 25.33 – 25.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000177239 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000036646 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Gonzalez DS, Karaveg K, Vandersall-Nairn AS, Lal A, Moremen KW (Aug 1999). "Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis". J Biol Chem. 274 (30): 21375–86. doi:10.1074/jbc.274.30.21375. PMID 10409699.
  6. Tremblay LO, Herscovics A (Nov 1999). "Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis". Glycobiology. 9 (10): 1073–8. doi:10.1093/glycob/9.10.1073. PMID 10521544.
  7. "Entrez Gene: MAN1B1 mannosidase, alpha, class 1B, member 1".

Further reading


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