Livia S. Eberlin

Livia Schiavinato Eberlin is a Brazilian analytical chemist who won a MacArthur "Genius" Fellowship for her research on the use of mass spectrometry to detect cancerous tissue.[1][2]

Education and career

Eberlin is the daughter of Marcos Nogueira Eberlin, a Brazilian chemist at the University of Campinas.[3] She was born in Campinas, and was a student at the University of Campinas herself; she earned her bachelor's degree there in 2007. During her undergraduate program, she did summer research in chemistry at Purdue University,[4] where her father also had research ties.[3] She continued at Purdue for her doctorate, and completed it in 2012; her dissertation, Developments in ambient mass spectrometry imaging and its applications in biomedical research and cancer diagnosis, was supervised by R. Graham Cooks.[4][5]

After postdoctoral research at Stanford University with Richard Zare, she joined the chemistry faculty at the University of Texas at Austin in 2012.[4]

Research

In her research, she developed a pen-like device, called the "MasSpec Pen" or "The Cancer Pen", that she claims can detect cancerous tissue by touching it during surgery, freezing and slicing it, and examining the slices under a microscope.[6] The pen allows surgeons to achieve a better understanding of which tissues are deemed harmful and should be removed. As a co-principal investigator, at the University of Texas at Austin, Eberlin has developed a way to detect thyroid cancer, in hours, without surgery. This test uses the same technique as her “MasSpecPen”, mass spectroscopy. It is two-thirds more accurate than the test already in use, fine-needle aspiration.[7] As well as her work on cancer diagnosis, Eberlin has also worked with Cooks and her father on the use of mass spectrometry to quickly detect counterfeit money.[3] Eberlin is concerned about the representation of women and diversity in science. In interviews, she has stressed the importance of women in higher levels of academia as well as leadership.[8]

Recognition

Eberlin was named a Forbes "30 Under 30" in 2015.[9] She won the Marion Milligan Mason Award of the American Association for the Advancement of Science in 2017. The award is given every two years to promising young female researchers in chemistry.[10] She won a MacArthur "Genius" Fellowship from the John D. and Catherine T. MacArthur Foundation. in 2018 for her research on the use of mass spectrometry "to differentiate more quickly and accurately diseased from healthy tissues during surgery".[1][2] She is the first UT Austin professor to win MacArthur grant this century.[11] The award consists of a $625,000 no-strings-attached grant. According to the foundation, this award goes to "extraordinarily talented and creative individuals as an investment in their potential".[12] She also won a Moore Inventor Fellowship in 2018.[13]

Selected publications

Research articles

  • Ifa, D. R., & Eberlin, L. S. (2016). Ambient ionization mass spectrometry for cancer diagnosis and surgical margin evaluation. Clinical chemistry, 62(1), 111-123. DOI: 10.1373/clinchem.2014.237172
  • Sans, M., Gharpure, K., Tibshirani, R., Zhang, J., Liang, L., Liu, J., ... & Eberlin, L. S. (2017). Metabolic markers and statistical prediction of serous ovarian cancer aggressiveness by ambient ionization mass spectrometry imaging. Cancer research, 77(11), 2903-2913.
  • Santagata, S., Eberlin, L. S., Norton, I., Calligaris, D., Feldman, D. R., Ide, J. L., ... & Orringer, D. A. (2014). Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery. Proceedings of the National Academy of Sciences, 111(30), 11121-11126. DOI:
  • Correa, D. N., Santos, J. M., Eberlin, L. S., Eberlin, M. N., & Teunissen, S. F. (2016). Forensic chemistry and ambient mass spectrometry: a perfect couple destined for a happy marriage? DOI:
  • Wu, C., Dill, A. L., Eberlin, L. S., Cooks, R. G., & Ifa, D. R. (2013). Mass spectrometry imaging under ambient conditions. Mass spectrometry reviews, 32(3), 218-243. DOI:
  • Eberlin, L. S., Norton, I., Orringer, D., Dunn, I. F., Liu, X., Ide, J. L., ... & Santagata, S. (2013). Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors. Proceedings of the National Academy of Sciences, 110(5), 1611-1616. DOI:
  • Eberlin, L. S., Norton, I., Dill, A. L., Golby, A. J., Ligon, K. L., Santagata, S., ... & Agar, N. Y. (2012). Classifying human brain tumors by lipid imaging with mass spectrometry. Cancer research, 72(3), 645-654. DOI: 10.1158/0008-5472.CAN-11-2465

References

  1. Livia S. Eberlin, MacArthur Foundation, retrieved 2018-10-04
  2. Wyllie, Julian (October 4, 2018), "Meet the Academics Who Nabbed This Year's MacArthur 'Genius' Grants", The Chronicle of Higher Education
  3. Bradley, David (2010), "Counterfeit Spectroscopy", ChemViews Magazine, ChemPubSoc Europe, doi:10.1002/chemv.201000020
  4. "About Livia", Livia S. Eberlin Research Group, University of Texas at Austin, retrieved 2018-10-04
  5. Eberlin, Livia S. (2012), "Developments in ambient mass spectrometry imaging and its applications in biomedical research and cancer diagnosis", Purdue e-Pubs, Purdue University, retrieved 2018-10-04
  6. Petrova, Magdalena (March 22, 2018), This 3-D printed pen lets surgeons detect cancer in 10 seconds, CNBC
  7. "New UT test detects cancer in hours; decreases need for surgery". KXAN.com. 2019-10-07. Retrieved 2019-10-08.
  8. "Dr. Livia S. Eberlin: "I Always Thought the Word 'Genius' Sounded Funny. How Can You Really Define What's Genius?"". Texas Monthly. 2018-10-16. Retrieved 2019-10-08.
  9. "30 Under 30". Forbes. 2015. Retrieved 8 October 2019.
  10. AAAS Marion Milligan Mason Award Recipients, American Association for the Advancement of Science, retrieved 2018-10-04
  11. "UT chemist Livia S. Eberlin wins MacArthur 'genius' grant". Statesman. Retrieved 8 October 2019.
  12. Haurwitz, Ralph K. M. "UT chemist Livia S. Eberlin wins MacArthur 'genius' grant". Austin American-Statesman. Retrieved 2019-10-08.
  13. https://cns.utexas.edu/news/ut-austin-chemist-livia-eberlin-named-a-moore-inventor-fellow
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