Kabat numbering scheme

The Kabat numbering scheme is a scheme for the numbering of amino acid residues in antibodies based upon variable regions. The scheme is useful when comparing these variable regions between antibodies.[1] Its foundations were laid by the American biomedical scientist Elvin A. Kabat, who started collecting and aligning amino acid sequences of human and mouse Bence Jones proteins and immunoglobulin light chains in 1969.

Another numbering scheme is the Chothia numbering system.