James Manley (disambiguation)

James Manley (born 1974) is a former American football defensive tackle.

James Manley or Manly may also refer to:

• James L. Manley (born 1949), professor of life sciences
• James R. Manley (1782–1851), American physician and professor of obstetrics
• James Manley (wrestler) (born 1958), American professional wrestler, better known by the ring name Jim Powers
• James Manly (born 1932), Canadian politician
• James Manly, sergeant in 3d Armored Cavalry Regiment during Mexican-American War