Hermann Blumgart

Hermann Ludwig Blumgart (1895-1977) was an American physician. He is considered by some as “the father of nuclear medicine” for his work with medical imaging by using small amounts of radioactive material to diagnose and treat a variety of diseases including cancer.[1] Blumgart was the first to use a radiotracer for a diagnostic procedure.[2]

Life and career

Blumgart was born into a Jewish household. He graduated from Harvard University in 1917[3] and Harvard Medical School in 1921.[4] He was a Harvard medical student working under the physiology pioneer Walter Cannon. At Harvard, he acquired a deep appreciation of the dynamics of physiology. Blumgart was especially interested in the circulation and knew that despite many ingenious attempts, no one had succeeded in measuring circulation time between any 2 points accurately and convincingly.[5] In 1924, he worked as investigator at the Thorndike Laboratories at Boston City Hospital.[1] In 1927, Blumgart and Soma Weiss used Bi214 to measure circulation time from one arm to the other in both normal and abnormal patients. This is the first time a radionuclide was employed in diagnostic medicine.[6] Between 1928 and 1962, he was the physician in chief at Beth Israel Hospital in Boston.[7][5]

Notable work

In 1925, Blumgart performed the first diagnostic procedure using radioactive indicators on humans.[8][9] Blumgart and his coworker Otto C. Yens, then a medical student, developed the first instrumentation used in a diagnostic procedure involving radioactive indicators. The instrumentation, a modified Wilson cloud chamber, turned out to be the detector most suitable for their purpose. The Blumgart-Yens modified cloud chamber is considered the birth of nuclear medicine instrumentation.[9] Blumgart and Yens used bismuth-214 to determine the arm -to- arm circulation time in patients.[10][11]

Legacy

In 1989, the Cardiovascular Council presented the Hermann Blumgart Award for outstanding achievement in the field of nuclear cardiology and service to the council. The award is still given to this day.[12]

References
  1. "Beth Israel Deaconess Medical Center". google.com. Retrieved 8 January 2019.
  2. Giussani, Augusto; Hoeschen, Christoph (2013-03-15). Imaging in Nuclear Medicine (Augusto Giussani, Christoph Hoeschen ed.). ISBN 9783642314155.
  3. Class Of 1917, Harvard University (1921). "Secretary's ... Report".
  4. Koren, Nathan (1973). Jewish Physicians: A Biographical Index. ISBN 9780706512694.
  5. Patton, Dennis D. "The Birth of Nuclear Medicine Instrumentation: Blumgart and Yens, 1925". snmjournals.org. PMID 12902429. Retrieved 8 January 2019.
  6. Carlson, Sten (1995). "A Glance At The History Of Nuclear Medicine". Acta Oncologica. 34 (8): 1095–1102. doi:10.3109/02841869509127236. PMID 8608034.
  7. Hellman, Samuel (2016-11-10). Learning While Caring: Reflections on a Half-Century of Cancer Practice, Research, Education, and Ethics. ISBN 9780190657000.
  8. Patton, DD (2003). "The birth of nuclear medicine instrumentation: Blumgart and Yens, 1925". J Nucl Med. 44 (8): 1362–5. PMID 12902429.
  9. Patton, DD (2003). "The birth of nuclear medicine instrumentation: Blumgart and Yens, 1925". Journal of Nuclear Medicine. 44 (8): 1362–5. PMID 12902429.
  10. Bleavins, Michael R.; Carini, Claudio; Jurima-Romet, Mallé; Rahbari, Ramin (2011-09-20). Biomarkers in Drug Development: A Handbook of Practice, Application, and Strategy (Michael R. Bleavins, Claudio Carini, Mallé Jurima-Romet, Ramin Rahbari ed.). ISBN 9781118210420.
  11. Knapp, F. F. (Russ); Dash, Ashutosh (2016-01-20). Radiopharmaceuticals for Therapy. ISBN 9788132226079.
  12. "Hermann L. Blumgart Award Recipients" (PDF). cms-plus.com. Retrieved 8 January 2019.
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