HES3

Hes family bHLH transcription factor 3 is a protein that in humans is encoded by the HES3 gene.[5]

HES3
Identifiers
AliasesHES3, bHLHb43, hes family bHLH transcription factor 3
External IDsOMIM: 609971 MGI: 104877 HomoloGene: 7358 GeneCards: HES3
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p36.31Start6,244,179 bp[1]
End6,245,578 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

390992

15207

Ensembl

ENSG00000173673

ENSMUSG00000028946

UniProt

Q5TGS1

Q61657

RefSeq (mRNA)

NM_001024598

NM_008237

RefSeq (protein)

NP_001019769

NP_032263

Location (UCSC)Chr 1: 6.24 – 6.25 MbChr 4: 152.29 – 152.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000173673 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028946 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Hes family bHLH transcription factor 3".

Further reading

  • Katoh M, Katoh M (August 2004). "Identification and characterization of human HES2, HES3, and HES5 genes in silico". International Journal of Oncology. 25 (2): 529–34. doi:10.3892/ijo.25.2.529. PMID 15254753.
  • Katoh M, Katoh M (August 2007). "Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer". International Journal of Oncology. 31 (2): 461–6. doi:10.3892/ijo.31.2.461. PMID 17611704.
  • Fukami M, Wada Y, Okada M, Kato F, Katsumata N, Baba T, Morohashi K, Laporte J, Kitagawa M, Ogata T (February 2008). "Mastermind-like domain-containing 1 (MAMLD1 or CXorf6) transactivates the Hes3 promoter, augments testosterone production, and contains the SF1 target sequence". The Journal of Biological Chemistry. 283 (9): 5525–32. doi:10.1074/jbc.M703289200. PMID 18162467.
  • Park DM, Jung J, Masjkur J, Makrogkikas S, Ebermann D, Saha S, Rogliano R, Paolillo N, Pacioni S, McKay RD, Poser S, Androutsellis-Theotokis A (2013). "Hes3 regulates cell number in cultures from glioblastoma multiforme with stem cell characteristics". Scientific Reports. 3: 1095. doi:10.1038/srep01095. PMC 3566603. PMID 23393614.
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