GALNT11

GALNT11
Identifiers
Aliases	GALNT11, GALNACT11, GALNAC-T11, polypeptide N-acetylgalactosaminyltransferase 11
External IDs	OMIM: 615130 MGI: 2444392 HomoloGene: 11126 GeneCards: GALNT11
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	152,122,347 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	25,265,918 bp[2]
Gene ontology
Molecular function	• transferase activity; • transferase activity, transferring glycosyl groups; • metal ion binding; • Notch binding; • carbohydrate binding; • polypeptide N-acetylgalactosaminyltransferase activity;
Cellular component	• integral component of membrane; • Golgi apparatus; • membrane; • Golgi membrane;
Biological process	• Notch signaling pathway; • cilium morphogenesis; • protein glycosylation; • protein O-linked glycosylation via threonine; • determination of left/right symmetry; • O-glycan processing; • Notch receptor processing; • regulation of Notch signaling pathway; • Notch signaling involved in heart development;
	Sources:Amigo / QuickGO
Orthologs
	63917
	231050
	ENSG00000178234
	ENSMUSG00000038072
	Q8NCW6
	Q921L8
	NM_001304514; NM_022087
	NM_144908; NM_001359890
NP_001291443; NP_071370; NP_001358387; NP_001358388; NP_001358389;
	NP_001358390; NP_001358391; NP_001358392; NP_001358393; NP_001358394; NP_001358395; NP_001358396; NP_001358397; NP_001358398; NP_001358399; NP_001358400; NP_001358401; NP_001358402; NP_001358403; NP_001358404
	NP_659157; NP_001346819
	Wikidata
View/Edit Human	View/Edit Mouse

Polypeptide N-acetylgalactosaminyltransferase 11 is an enzyme that in humans is encoded by the GALNT11 gene.[5][6]

The GALNT11 gene contains 10 exons.[7] An important paralog of this gene is GALNTL5.[8]

References

GRCh38: Ensembl release 89: ENSG00000178234 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000038072 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, Behrens J, Mandel U, Keck B, Schafer MA, Haselmann K, Zubarev R, Roepstorff P, Burchell JM, Taylor-Papadimitriou J, Hollingsworth MA, Clausen H (Jun 2002). "Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila". J Biol Chem. 277 (25): 22623–38. doi:10.1074/jbc.M202684200. PMID 11925450.
"Entrez Gene: GALNT11 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)".
"UDP-N-ACETYL-ALPHA-D-GALACTOSAMINE:POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 11; GALNT11".
"GALNT11 Gene (Protein Coding)".

"Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000178234 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038072 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11925450-5] Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, Behrens J, Mandel U, Keck B, Schafer MA, Haselmann K, Zubarev R, Roepstorff P, Burchell JM, Taylor-Papadimitriou J, Hollingsworth MA, Clausen H (Jun 2002). "Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila". J Biol Chem. 277 (25): 22623–38. doi:10.1074/jbc.M202684200. PMID 11925450.

[entrez-6] "Entrez Gene: GALNT11 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)".

[7] "UDP-N-ACETYL-ALPHA-D-GALACTOSAMINE:POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 11; GALNT11".

[8] "GALNT11 Gene (Protein Coding)".

GALNT11

References

Further reading