Francois Balloux

Francois Balloux is the Director of the UCL Genetics Institute,[1] and a Professor of Computational Systems Biology at University College London.[2]

Francois Balloux

He earned a Master's degree in 1996 and a Doctorate in 2000 from the University of Lausanne. He then completed postdoctoral research at the University of Edinburgh. Balloux was a Lecturer at the University of Cambridge, between 2002 and 2007, before taking a position as a Reader in Infectious Disease Epidemiology at Imperial College London. In 2012, Balloux became a Professor at University College London.[2]

His research lies at the interface of Genomics, Epidemiology, Evolution and Ecology. The main focus of his work is on the reconstruction of disease outbreaks and epidemics of human and wildlife pathogens,[3][4][5] and the emergence of antimicrobial resistance.[6][7][8] His work has been cited over 20,000 times on Google Scholar.[9]

Together with his colleague Dr Lucy Van Dorp, they led a team of researchers in the analysis of the first large-scale analysis of 7666 complete SARS-Cov-2 genomes, the agent of the COVID-19 pandemic. The work confirmed a host jump of SARS-Cov-2 into the human population in late 2019, extensive global transmission from early on in the pandemic, and identified a list of 198 candidate mutations for ongoing adaptation to its novel human host.[10]

References

  1. UCL (2019-02-08). "UCL Genetics Institute". UCL Division of Biosciences. Retrieved 2020-04-07.
  2. "Professor Francois Balloux | UCL Division of Biosciences - UCL - London's Global University". ucl.ac.uk. Retrieved 2020-03-15.
  3. Wang, Ruobing; van Dorp, Lucy; Shaw, Liam P.; Bradley, Phelim; Wang, Qi; Wang, Xiaojuan; Jin, Longyang; Zhang, Qing; Liu, Yuqing; Rieux, Adrien; Dorai-Schneiders, Thamarai (2018-03-21). "The global distribution and spread of the mobilized colistin resistance gene mcr-1". Nature Communications. 9 (1): 1179. Bibcode:2018NatCo...9.1179W. doi:10.1038/s41467-018-03205-z. ISSN 2041-1723. PMC 5862964. PMID 29563494.
  4. O’Hanlon, Simon J.; Rieux, Adrien; Farrer, Rhys A.; Rosa, Gonçalo M.; Waldman, Bruce; Bataille, Arnaud; Kosch, Tiffany A.; Murray, Kris A.; Brankovics, Balázs; Fumagalli, Matteo; Martin, Michael D. (2018-05-11). "Recent Asian origin of chytrid fungi causing global amphibian declines". Science. 360 (6389): 621–627. Bibcode:2018Sci...360..621O. doi:10.1126/science.aar1965. ISSN 0036-8075. PMC 6311102. PMID 29748278.
  5. Eldholm, Vegard; Pettersson, John H.-O.; Brynildsrud, Ola B.; Kitchen, Andrew; Rasmussen, Erik Michael; Lillebaek, Troels; Rønning, Janne O.; Crudu, Valeriu; Mengshoel, Anne Torunn; Debech, Nadia; Alfsnes, Kristian (2016-11-29). "Armed conflict and population displacement as drivers of the evolution and dispersal of Mycobacterium tuberculosis". Proceedings of the National Academy of Sciences. 113 (48): 13881–13886. doi:10.1073/pnas.1611283113. ISSN 0027-8424. PMC 5137683. PMID 27872285.
  6. Balloux, Francois; Brønstad Brynildsrud, Ola; van Dorp, Lucy; Shaw, Liam P.; Chen, Hongbin; Harris, Kathryn A.; Wang, Hui; Eldholm, Vegard (2018). "From Theory to Practice: Translating Whole-Genome Sequencing (WGS) into the Clinic". Trends in Microbiology. 26 (12): 1035–1048. doi:10.1016/j.tim.2018.08.004. PMC 6249990. PMID 30193960.
  7. Shaw, Liam P.; Bassam, Hassan; Barnes, Chris P.; Walker, A. Sarah; Klein, Nigel; Balloux, Francois (2019). "Modelling microbiome recovery after antibiotics using a stability landscape framework". The ISME Journal. 13 (7): 1845–1856. doi:10.1038/s41396-019-0392-1. ISSN 1751-7370. PMC 6591120. PMID 30877283.
  8. Eldholm, Vegard; Rieux, Adrien; Monteserin, Johana; Lopez, Julia Montana; Palmero, Domingo; Lopez, Beatriz; Ritacco, Viviana; Didelot, Xavier; Balloux, Francois (2016-08-09). Jit, Mark (ed.). "Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis". eLife. 5: e16644. doi:10.7554/eLife.16644. ISSN 2050-084X. PMID 27502557.
  9. "Francois Balloux - Google Scholar Citations". scholar.google.co.uk. Retrieved 2020-04-07.
  10. van Dorp, Lucy; Acman, Mislav; Richard, Damien; Shaw, Liam P.; Ford, Charlotte E.; Ormond, Louise; Owen, Christopher J.; Pang, Juanita; Tan, Cedric C. S.; Boshier, Florencia A. T.; Ortiz, Arturo Torres (2020-05-05). "Emergence of genomic diversity and recurrent mutations in SARS-CoV-2". Infection, Genetics and Evolution: 104351. doi:10.1016/j.meegid.2020.104351. ISSN 1567-1348. PMC 7199730. PMID 32387564.
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