Ernst Knobil

Ernst Knobil (September 20, 1926 – April 13, 2000) was a scientist known for his studies of endocrinology.[1]

Knobil's research into hormonal regulation in primates led to his discovery of growth hormone's species-specific effects. These discoveries led to the first treatment of Growth hormone deficiency.

Knobil is also credited with discovering the key role of pulsatile Gonadotropin-releasing hormone and estrogen feedback during the menstrual cycle. This work today forms the basis of reproductive endocrinology and enabled development of the world's first hormonal contraceptives.

In addition to being the author of 217 scientific papers, he was the editor of several reference books in endocrinology and reproduction, including The Handbook of Physiology (1974), The Physiology of Reproduction (1988, 1994), and The Encyclopedia of Reproduction (1998). In addition to his numerous scientific contributions, Ernst was a visionary leader in the field of endocrinology and a wonderful mentor and friend to the many people who were privileged to work closely with him.(1)