EPS8L1

Epidermal growth factor receptor kinase substrate 8-like protein 1 is an enzyme that in humans is encoded by the EPS8L1 gene.[5][6]

EPS8L1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEPS8L1, DRC3, EPS8R1, PP10566, EPS8 like 1
External IDsOMIM: 614987 MGI: 1914675 HomoloGene: 15767 GeneCards: EPS8L1
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.42Start55,072,020 bp[1]
End55,087,923 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

54869

67425

Ensembl

ENSG00000131037

ENSMUSG00000006154

UniProt

Q8TE68

Q8R5F8

RefSeq (mRNA)

NM_017729
NM_133180
NM_139204

NM_001290416
NM_026146
NM_001374622

RefSeq (protein)

NP_060199
NP_573441

NP_001277345
NP_080422
NP_001361551

Location (UCSC)Chr 19: 55.07 – 55.09 MbChr 7: 4.46 – 4.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Several alternatively spliced transcript variants encoding different isoforms exist.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000131037 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000006154 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C (Mar 2003). "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure". Genomics. 81 (2): 234–44. doi:10.1016/S0888-7543(03)00002-8. PMID 12620401.
  6. "Entrez Gene: EPS8L1 EPS8-like 1".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.