EP400

E1A-binding protein p400 is a protein that in humans is encoded by the EP400 gene.[5][6][7]

EP400
Identifiers
AliasesEP400, CAGH32, P400, TNRC12, E1A binding protein p400
External IDsOMIM: 606265 MGI: 1276124 HomoloGene: 38779 GeneCards: EP400
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q24.33Start131,949,942 bp[1]
End132,080,460 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

57634

75560

Ensembl

ENSG00000183495

ENSMUSG00000029505

UniProt

Q96L91

Q8CHI8

RefSeq (mRNA)

NM_015409

NM_029337
NM_173066

RefSeq (protein)

NP_056224

NP_083613
NP_775089

Location (UCSC)Chr 12: 131.95 – 132.08 MbChr 5: 110.66 – 110.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

EP400 has been shown to interact with Transformation/transcription domain-associated protein,[6] RuvB-like 1[6] and Myc.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000183495 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029505 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA (Jul 1997). "cDNAs with long CAG trinucleotide repeats from human brain". Hum Genet. 100 (1): 114–22. doi:10.1007/s004390050476. PMID 9225980.
  6. Fuchs M, Gerber J, Drapkin R, Sif S, Ikura T, Ogryzko V, Lane WS, Nakatani Y, Livingston DM (Aug 2001). "The p400 complex is an essential E1A transformation target". Cell. 106 (3): 297–307. doi:10.1016/S0092-8674(01)00450-0. PMID 11509179.
  7. "Entrez Gene: EP400 E1A binding protein p400".

Further reading


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