Doug Crawford

John Douglas (Doug) Crawford is a Canadian neuroscientist and the scientific director of the Vision: Science to Applications(VISTA) program. He is a professor at York University where he holds the Canada Research Chair in Visuomotor Neuroscience[1] and the title of Distinguished Research Professor in Neuroscience.

Profile picture of John Douglas (Doug) Crawford

Biography

Crawford completed his PhD in Physiology with Tutis Vilis at Western University in 1993 where he was awarded the Governor General's Academic Gold medal.[2] He then spent two years as a Medical Research Council of Canada post-doctoral fellow with Daniel Guitton at the Montreal Neurological Institute. He joined York University's Department of Psychology and York Centre for Vision Research as an assistant professor in 1995, where he was awarded an Alfred P Sloan Fellowship[3] and Canadian Medical Research Council Scholarship. He became an Associate Professor in 1999, Full Professor in 2005, and Distinguished Research Professor in 2013.[4] He has been awarded several research prizes including the 1995 Polanyi Prize in Physiology/Medicine,[5] the 2002 CIFAR Young Explorer Award (awarded to the "top 20 young investigators in Canada"), the 2004 Steacie prize (awarded to "a scientist or engineer of 40 years of age or less for outstanding scientific research carried out in Canada."),[6] the 2016 Canadian Physiological Society Sarrazin Award.,[7] and the 2018 York President's Research Excellence Award.[8]

Leadership and training

Crawford was the founding national coordinator of the Canadian Action and Perception Network (CAPnet),[9] the founding Canadian director of the Brain in Action International Research Training Program,[10] and the founding coordinator of the York Neuroscience Graduate Diploma Program.[11] He founded York's neurophysiology laboratories,[12] was a founding member of Melvyn A. Goodale's CIHR Group for Action and Perception [13] and founding co-principal investigator for the CIHR Strategic Training Program in Vision Health Research.[14] He is currently the scientific director of Vision: Science to Applications(VISTA),[15] a Canada First Research Excellence Fund supported research program that integrates York University's biological and computational vision research.

Crawford has supervised over 60 graduate students and post-doctorals, many graduating to successful careers in academia, medicine, and industry.[16] Among his noteworthy former trainees are Pieter Medendorp, Director of the Donders Centre for Cognition in Nijmegen,[17] Julio Martinez-Trujillo, Provincial Endowed Academic Chair in Autism at Western University,[18] Gunnar Blohm, Queens Professor and Founding Co-Director of the International Summer School in Computational Sensory-Motor Neuroscience,[19] Aarlenne Khan, Canada Research Chair in Vision and Action at Université de Montréal,[20] and Denise Henriques, York Professor and Director of the NSERC CREATE Brain in Action Program.[21]

Research

Crawford's research investigates the neural mechanisms of visuospatial memory and sensorimotor transformations for eye, head, and hand motion.[22][23] A recurrent theme in his work is that early representations of object locations are stored in sensory coordinates, updated during self-motion, and then used to generate coordinated motion of different body parts[24] Some noteworthy findings and discoveries by Crawford and co-workers include:

  • the first recordings of 3D Vestibulo–ocular reflex axes and Listing's law during head rotation[25]
  • the discovery of the midbrain neural integrator for vertical and torsional components of the Vestibulo-ocular reflex and saccades[26]
  • the first demonstration that the human parietal lobe retains and updates saccade and reach goals in gaze-centered coordinates,[27][28]
  • the use of stimulation-evoked eye-head movements to show that the superior colliculus encodes gaze goals in retinal coordinates,[29] whereas frontal cortex employs multiple coordinate frames[30]
  • the first demonstration that ocular dominance is not fixed, but reverses for left and right visual stimuli,[31]
  • a demonstration of the influence of binocular eye position and Listing's law on stereopsis[32]
  • the discovery of another midbrain neural integrator for 3D head orientation[33]
  • the use of optimal integration theory to explain change blindness during saccades [34]
  • the use of fMRI and TMS to map saccade vs. reach function in human posterior parietal cortex [35]
  • the use of TMS to show that both frontal and parietal cortex are involved the Transsaccadic memory of multiple visual features.[36]
  • the discovery that remembered visual stimuli are continuously updated across the superior colliculus during smooth pursuit eye movements,[37]

Crawford and colleagues have also applied this research to understand the mechanisms behind neurological disorders such as gaze paretic nystagmus, cervical dystonia[38] and optic ataxia.[39]

References

  1. "York U. Psychologist Doug Crawford wins Canada Research Chair in visual functions of the brain | York Media Relations". news.yorku.ca. Retrieved 2018-04-03.
  2. https://www.gg.ca/honour.aspx?id=5775&t=1&ln=Crawford
  3. "Past Fellows". sloan.org. Retrieved 2018-04-03.
  4. http://yfile.news.yorku.ca/2013/05/07/two-profs-awarded-2013-distinguished-research-professor-title/
  5. http://cou.on.ca/about/awards/john-charles-polanyi/prize-winners/
  6. http://www.steacieprize.ca/recipients_e.html
  7. http://www.cpsscp.ca/sarrazin-award-lectureship
  8. http://yfile.news.yorku.ca/2018/05/16/professors-doug-crawford-and-sapna-sharma-honoured-with-presidents-research-awards/
  9. "Western, York and Queens joint neuroscience initiative | Robarts Research". www.robarts.ca. Retrieved 2018-04-03.
  10. "DFG, German Research Foundation - A spotlight on: 'Brain in Action'". www.dfg.de. Retrieved 2018-04-03.
  11. "SIGNAL/NOISE newsletter" (PDF).
  12. url=http://health.yorku.ca/health-profiles/index.php?mid=6957
  13. url=http://webapps.cihr-irsc.gc.ca/funding/detail_e?pResearchId=7998385&p_version=CRIS&p_language=E&p_session_id=
  14. url=http://webapps.cihr-irsc.gc.ca/funding/detail_e?pResearchId=7979480&p_version=CRIS&p_language=E&p_session_id=
  15. "World Leading Vision Research Program Receives Canada's Premiere Grant | York Media Relations". news.yorku.ca. Retrieved 2018-04-03.
  16. "The Visuomotor Neuroscience Lab - Alumni". www.yorku.ca. Retrieved 2018-04-03.
  17. https://www.ru.nl/english/people/medendorp-w/
  18. http://www.robarts.ca/dr-julio-martinez-trujillo-appointed-academic-chair-autism
  19. http://www.compneurosci.com/blohm.html
  20. http://www.opto.umontreal.ca/visattac/en/links.html
  21. http://deniseh.lab.yorku.ca/
  22. Crawford, JD; Martinez-Trujillo, JC; Klier, EM (2003). "Neural control of three-dimensional eye and head movements". Current Opinion in Neurobiology. 13 (6): 655–662. doi:10.1016/j.conb.2003.10.009. ISSN 0959-4388. PMID 14662365.
  23. Crawford, J. D.; Medendorp, W. P.; Marotta, J. J. (2004). "Spatial Transformations for Eye–Hand Coordination". Journal of Neurophysiology. 92 (1): 10–19. doi:10.1152/jn.00117.2004. ISSN 0022-3077. PMID 15212434.
  24. Crawford, J. Douglas; Henriques, Denise Y.P.; Medendorp, W. Pieter (2011). "Three-Dimensional Transformations for Goal-Directed Action". Annual Review of Neuroscience. 34 (1): 309–331. doi:10.1146/annurev-neuro-061010-113749. ISSN 0147-006X. PMID 21456958.
  25. Crawford, J. D.; Vilis, T. (1991). "Axes of eye rotation and Listing's law during rotations of the head". Journal of Neurophysiology. 65 (3): 407–423. doi:10.1152/jn.1991.65.3.407. ISSN 0022-3077. PMID 2051188. S2CID 18736605.
  26. Crawford, J.; Cadera, W.; Vilis, T. (1991). "Generation of torsional and vertical eye position signals by the interstitial nucleus of Cajal". Science. 252 (5012): 1551–1553. doi:10.1126/science.2047862. ISSN 0036-8075. PMID 2047862. S2CID 15724175.
  27. Henriques, D. Y.; Klier, E. M.; Smith, M. A.; Lowy, D.; Crawford, J. D. (1998-02-15). "Gaze-centered remapping of remembered visual space in an open-loop pointing task". The Journal of Neuroscience. 18 (4): 1583–1594. doi:10.1523/JNEUROSCI.18-04-01583.1998. ISSN 0270-6474. PMC 6792733. PMID 9454863.
  28. Medendorp, W. Pieter; Goltz, Herbert C.; Vilis, Tutis; Crawford, J. Douglas (2003-07-16). "Gaze-centered updating of visual space in human parietal cortex". The Journal of Neuroscience. 23 (15): 6209–6214. doi:10.1523/JNEUROSCI.23-15-06209.2003. ISSN 1529-2401. PMC 6740538. PMID 12867504.
  29. Klier, Eliana M.; Wang, Hongying; Crawford, J. Douglas (2001). "The superior colliculus encodes gaze goals in retinal coordinates". Nature Neuroscience. 4 (6): 627–632. doi:10.1038/88450. ISSN 1097-6256. PMID 11369944.
  30. Martinez-Trujillo, Julio C.; Medendorp, W.Pieter; Wang, Hongying; Crawford, J.Douglas (2004). "Frames of Reference for Eye-Head Gaze Commands in Primate Supplementary Eye Fields". Neuron. 44 (6): 1057–1066. doi:10.1016/j.neuron.2004.12.004. ISSN 0896-6273. PMID 15603747.
  31. Khan, Aarlenne Z; Crawford, J.Douglas (2001). "Ocular dominance reverses as a function of horizontal gaze angle". Vision Research. 41 (14): 1743–1748. doi:10.1016/S0042-6989(01)00079-7. ISSN 0042-6989. PMID 11369037.
  32. Schreiber, Kai; Crawford, J. Douglas; Fetter, Michael; Tweed, Douglas (2001). "The motor side of depth vision". Nature. 410 (6830): 819–822. doi:10.1038/35071081. ISSN 0028-0836. PMID 11298450.
  33. Klier, E. M. (2002). "Midbrain Control of Three-Dimensional Head Orientation". Science. 295 (5558): 1314–1316. doi:10.1126/science.1067300. ISSN 0036-8075. PMID 11847347.
  34. Niemeier, Matthias; Crawford, J. Douglas; Tweed, Douglas B. (2003). "Optimal transsaccadic integration explains distorted spatial perception". Nature. 422 (6927): 76–80. doi:10.1038/nature01439. ISSN 0028-0836. PMID 12621435.
  35. Vesia, M.; Prime, S. L.; Yan, X.; Sergio, L. E.; Crawford, J. D. (2010). "Specificity of Human Parietal Saccade and Reach Regions during Transcranial Magnetic Stimulation". Journal of Neuroscience. 30 (39): 13053–13065. doi:10.1523/JNEUROSCI.1644-10.2010. ISSN 0270-6474. PMC 6633525. PMID 20881123.
  36. Prime, S. L.; Vesia, M.; Crawford, J. D. (2011). "Cortical mechanisms for trans-saccadic memory and integration of multiple object features". Philosophical Transactions of the Royal Society B: Biological Sciences. 366 (1564): 540–553. doi:10.1098/rstb.2010.0184. ISSN 0962-8436. PMC 3030828. PMID 21242142.
  37. Dash, Suryadeep; Yan, Xiaogang; Wang, Hongying; Crawford, John Douglas (2015). "Continuous Updating of Visuospatial Memory in Superior Colliculus during Slow Eye Movements". Current Biology. 25 (3): 267–274. doi:10.1016/j.cub.2014.11.064. ISSN 0960-9822. PMID 25601549.
  38. Shaikh, Aasef G.; Zee, David S.; Crawford, J. Douglas; Jinnah, Hyder A. (2016). "Cervical dystonia: a neural integrator disorder". Brain. 139 (10): 2590–2599. doi:10.1093/brain/aww141. ISSN 0006-8950. PMC 5840887. PMID 27324878.
  39. Khan, A Z; Pisella, L; Vighetto, A; Cotton, F; Luauté, J; Boisson, D; Salemme, R; Crawford, J D; Rossetti, Y (2005). "Optic ataxia errors depend on remapped, not viewed, target location". Nature Neuroscience. 8 (4): 418–420. doi:10.1038/nn1425. ISSN 1097-6256. PMID 15768034.
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