Dehydroaltenusin

Dehydroaltenusin is an inhibitor of mammalian DNA polymerase α.[1] It has been isolated from the fungus Alternaria tenuis.[1]

Dehydroaltenusin
Names
IUPAC name
3,7-Dihydroxy-9-methoxy-4a-methylbenzo[c]chromene-2,6-dione
Identifiers
3D model (JSmol)
ChemSpider
Properties
C15H12O6
Molar mass 288.255 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Mizushina, Y; Maeda, N; Kuriyama, I; Yoshida, H (2011). "Dehydroaltenusin is a specific inhibitor of mammalian DNA polymerase α". Expert Opinion on Investigational Drugs. 20 (11): 1523–34. doi:10.1517/13543784.2011.619977. PMID 21923630.


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