De novo
In general usage, de novo (literally 'of new') is Latin expression used in English to mean 'from the beginning', 'anew'.
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De novo may also refer to:
Biology
- De novo, mutation, an alteration in a gene that is present for the first time in one family member as a result of a mutation in a germ cell (egg or sperm) of one of the parents or in the fertilized egg itself
- De novo, protein design, the creation of a protein sequence that is not based on existing, natural sequences
- De novo protein structure prediction, the prediction of a protein's 3D structure, based only on its sequence
- De novo synthesis of complex molecules from simple molecules in chemistry
- De novo transcriptome assembly, the method of creating a transcriptome without a reference genome
- De novo gene birth, the emergence of genes from non-coding sequence
Other
- De novo review, an appellate standard of review for legal issues
- Trial de novo, or a new trial in the legal system
- De novo bank, a state bank that has been in operation for five years or less
- De Novo, a public housing estate in Kai Tak, Hong Kong
- Denovo (band), a 1980s Italian new wave group
- Denovo, a supercomputer project that simulates nuclear reactions
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