Chromatin accessibility complex 1

CHRAC1
Identifiers
Aliases	CHRAC1, CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1, chromatin accessibility complex 1, chromatin accessibility complex subunit 1
External IDs	OMIM: 607268 MGI: 2135796 HomoloGene: 41174 GeneCards: CHRAC1
Gene location (Human)
Chr.	Chromosome 8 (human)[1]
End	140,517,154 bp[1]
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)[2]
End	73,097,554 bp[2]
Gene ontology
Molecular function	• transferase activity; • DNA binding; • DNA-directed DNA polymerase activity; • nucleotidyltransferase activity; • GO:0001948 protein binding; • protein heterodimerization activity;
Cellular component	• epsilon DNA polymerase complex; • cell nucleus; • CHRAC;
Biological process	• DNA biosynthetic process; • chromatin remodeling; • nucleosome mobilization; • heterochromatin organization involved in chromatin silencing;
	Sources:Amigo / QuickGO
Orthologs
	54108
	93696
	ENSG00000104472
	ENSMUSG00000068391
	Q9NRG0
	Q9JKP8
	NM_017444
	NM_053068
	NP_059140
	NP_444298
	Wikidata
View/Edit Human	View/Edit Mouse

Chromatin accessibility complex 1 is a protein that in humans is encoded by the CHRAC1 gene. [5]

Function

CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

References

GRCh38: Ensembl release 89: ENSG00000104472 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000068391 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Chromatin accessibility complex 1". Retrieved 2016-10-26.

Chromatin accessibility complex 1

Function

References

Further reading