CTDSPL

CTD small phosphatase-like protein is an enzyme that in humans is encoded by the CTDSPL gene.[5][6][7]

CTDSPL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCTDSPL, C3orf8, HYA22, PSR1, RBSP3, SCP3, CTD small phosphatase like
External IDsOMIM: 608592 MGI: 1916524 HomoloGene: 48881 GeneCards: CTDSPL
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3p22.2Start37,861,880 bp[1]
End37,984,469 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

10217

69274

Ensembl

ENSG00000144677

ENSMUSG00000047409

UniProt

O15194

P58465

RefSeq (mRNA)

NM_005808
NM_001008392

NM_133710

RefSeq (protein)

NP_001008393
NP_005799

NP_598471

Location (UCSC)Chr 3: 37.86 – 37.98 MbChr 9: 118.93 – 119.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

CTDSPL has been shown to interact with SNAI1.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000144677 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000047409 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ishikawa S, Kai M, Tamari M, Takei Y, Takeuchi K, Bandou H, Yamane Y, Ogawa M, Nakamura Y (Aug 1997). "Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line". DNA Res. 4 (1): 35–43. doi:10.1093/dnares/4.1.35. PMID 9179494.
  6. Protopopov A, Kashuba V, Zabarovska VI, Muravenko OV, Lerman MI, Klein G, Zabarovsky ER (Jan 2003). "An integrated physical and gene map of the 3.5-Mb chromosome 3p21.3 (AP20) region implicated in major human epithelial malignancies". Cancer Res. 63 (2): 404–12. PMID 12543795.
  7. "Entrez Gene: CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like".
  8. Wu, Yadi; Evers B Mark; Zhou Binhua P (Jan 2009). "Small C-terminal domain phosphatase enhances snail activity through dephosphorylation". J. Biol. Chem. United States. 284 (1): 640–8. doi:10.1074/jbc.M806916200. ISSN 0021-9258. PMC 2610500. PMID 19004823.

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.