CORO1C

Coronin-1C is a protein that in humans is encoded by the CORO1C gene.[5][6][7]

CORO1C
Identifiers
AliasesCORO1C, HCRNN4, coronin 1C
External IDsOMIM: 605269 MGI: 1345964 HomoloGene: 56537 GeneCards: CORO1C
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q24.11Start108,645,109 bp[1]
End108,731,596 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23603

23790

Ensembl

ENSG00000110880

ENSMUSG00000004530

UniProt

Q9ULV4

Q9WUM4

RefSeq (mRNA)

NM_001105237
NM_001276471
NM_014325

NM_011779

RefSeq (protein)

NP_001098707
NP_001263400
NP_055140

NP_035909

Location (UCSC)Chr 12: 108.65 – 108.73 MbChr 5: 113.84 – 113.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000110880 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000004530 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Okumura M, Kung C, Wong S, Rodgers M, Thomas ML (Oct 1998). "Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein". DNA Cell Biol. 17 (9): 779–87. doi:10.1089/dna.1998.17.779. PMID 9778037.
  6. de Hostos EL (Oct 1999). "The coronin family of actin-associated proteins". Trends Cell Biol. 9 (9): 345–50. doi:10.1016/S0962-8924(99)01620-7. PMID 10461187.
  7. "Entrez Gene: CORO1C coronin, actin binding protein, 1C".

Further reading


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