CLEC9A
C-type lectin domain family 9 member A is a protein that in humans is encoded by the CLEC9A gene.[5]
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| Aliases | CLEC9A, DNGR1, UNQ9341, CD370, DNGR-1, C-type lectin domain family 9 member A, C-type lectin domain containing 9A | ||||||||||||||||||||||||
| External IDs | OMIM: 612252 MGI: 2444608 HomoloGene: 52106 GeneCards: CLEC9A | ||||||||||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||||||||||
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| Location (UCSC) | Chr 12: 10.03 – 10.07 Mb | Chr 6: 129.41 – 129.42 Mb | |||||||||||||||||||||||
| PubMed search | [3] | [4] | |||||||||||||||||||||||
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Function
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[6]
References
- GRCh38: Ensembl release 89: ENSG00000197992 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000046080 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: C-type lectin domain family 9 member A". Retrieved 2016-06-02.
- Zanders, Edward D. (2015-11-09). Human Drug Targets: A Compendium for Pharmaceutical Discovery. John Wiley & Sons. ISBN 978-1-118-84985-9.
Further reading
- Huysamen C, Willment JA, Dennehy KM, Brown GD (2008). "CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes". J. Biol. Chem. 283 (24): 16693–701. doi:10.1074/jbc.M709923200. PMC 2562446. PMID 18408006.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human C-type lectin domain family 9 member A (CLEC9A)
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