Bocasan

Bocasan was an oral wound cleanser manufactured in the United Kingdom by Knox Laboratories Ltd of London from 19601975,[1] before being rebranded as an Oral-B product [2]

Bocasan dental rinse front
Bocasan dental rinse back

Production of Bocasan appears to have ceased by 2003. A similar product, Amosan was available for a period before also ceasing production in 2010. As of 2013, a Dutch pharmacy offers the same formulation under the name Bikosan[3]

It was used to aid treatment, in adults or children over 5 years old, of periodontal conditions such as canker sores, denture irritation, orthodontic irritation, or after dental procedures.

Bocasan was packaged in a 1.7 gram envelope, and contained 69.72% sodium perborate monohydrate and 29.68% sodium hydrogen tartrate anhydrous. To use, the contents were dissolved in 30 cubic centimetres of warm water. Half the amount was swilled around the mouth for two minutes and discarded, and the procedure repeated with the remainder. Treatment was recommended three times a day after meals.

A 1979 double-blind crossover study [4] suggests that hydrogen peroxide, which is released during the use of this product, may prevent or retard colonization and multiplication of anaerobic bacteria, such as those that inhabit oral wounds.

Drug facts

  • Active ingredient: Sodium perborate monohydrate
  • Inactive ingredients: Sodium hydrogen tartrate
  • Purpose: Oral cleanser
  • Normal use: Use up to times daily, after meals or as directed by a dentist

References

  1. http://www.culturegrid.org.uk/static/showResource/3051671
  2. Medicines: The Comprehensive Guide edited by Dr. Ian Morton, Judith M. Hall. Royal Society of Medicine. Bloomsbury Publishing, London, 2002. Pg 118
  3. https://www.bik-bik.com/info/14/bikosan-replaces-bocasan
  4. "Effect of hydrogen peroxide on developing plaque and gingivitis in man". Journal of Clinical Periodontology. 6 (2): 115–30. April 1979. doi:10.1111/j.1600-051x.1979.tb02190.x. PMID 379049.


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