Benzthiazide

Benzthiazide (BAN/INN, also known as benzothiazide; trade names Aquatag, Dihydrex, Diucen, Edemax, Exna, Foven and others[1]) is a thiazide diuretic used in the treatment of high blood pressure and edema. It is no longer available in the United States.

Benzthiazide
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability60 to 70%
Protein binding30%
Elimination half-life5 to 15 hours
ExcretionRenal
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.874
Chemical and physical data
FormulaC15H14ClN3O4S3
Molar mass431.92 g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

In the United Kingdom, it was also sold in combination with the potassium-sparing diuretic triamterene under the trade name Dytide.[2] The same combination is still available in Switzerland as Dyrenium compositum.[3]

References

  1. David J. Triggle; C. R. Ganellin; F. MacDonald (1996). Dictionary of Pharmacological Agents. 1. Boca Raton: Chapman & Hall/CRC. p. 246. ISBN 0-412-46630-9. Retrieved on August 29, 2008 through Google Book Search.
  2. "Triamterene and Benzthiazide". PatientUK. 2005. Retrieved 2008-08-29.
  3. "Dyrenium compositum". Doetsch Grether. n.d. Archived from the original on February 11, 2007. Retrieved 2008-08-29.


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