Balaram Mukhopadhyay

Balaram Mukhopadhyay (Bengali: বলরাম মুখোপাধ্যায়: born 1973) is a Bengali Indian carbohydrate chemist and a professor at the department of chemical sciences of the Indian Institute of Science Education and Research, Kolkata.[1] Balaram is mainly known for his work in the field of synthetic carbohydrate chemistry.[2] He was given the Excellence in Carbohydrate Research Award by the Association of Carbohydrate Chemists and Technologists India (ACCTI) in 2018 for his contribution towards field of carbohydrate.

বলরাম মুখোপাধ্যায়

Biography
Mukhopadhyay and coworkers

Balaram Mukhopadhyay, born on January 12, 1973 in Bankura, a district town in the Indian state West Bengal, graduated with honors in chemistry from the Bankura Christian College in 1994 and followed it up with a master's degree from the Burdwan university in 1996. His journey with the world of carbohydrates is started when he enrolled for doctoral studies at the Indian Association For The Cultivation Of Science(IACS), Kolkata, under the guidance of Prof. Nirmolendu Roy and after securing a PhD in 2001, he moved to the UK for the post-doctoral studies, under the supervision of Robert A Field of the University of East Anglia, Norwich, UK (2001 - 2005).[3] After 4 years of Post-doctoral studies, Balaram joined as a Scientist-C at the Medicinal and Process Chemistry Division in Central Drug Research Institute (CDRI), Lucknow. He left CDRI at 2008 and joined as an Assistant professor at Indian Institute of Science Education and Research, Kolkata (IISER Kolkata), where he now holds a position of Professor.[4] At IISER, he heads a laboratory, named Sweet Lab, where he hosts several researchers.[5]

Balaram focuses his research mainly in oligosaccharide synthesis and published a number of articles. Later he also explore the fields like Glyco-nanoparticles, Supramolecular chemistry of carbohydrate gels and crystals, Carbohydrate protein interaction.[6]

He becomes a member of the Editorial Board of the international peer reviewed scientific journal Carbohydrate Research in 2017.[7]

Career

Academic background[8]
  1. PhD (Chemical Sciences), IACS (Jadavpur University), 2001
  2. MSc (Chemistry (Organic Chemistry Special)), Burdwan University, 1996
  3. BSc (Chemistry (Honours), Physics, Mathematics), Bankura Christian College (Burdwan University), 1994
  4. Higher Secondary (Physics, Chemistry, Mathematics, Biology), Bankura Christian College (WBCHSE), 1991
  5. Madhyamik (Bengali, English, Physical Science, Life Science, Mathematics, History, Geography), Bankura Zilla School (WBBSE), 1989

Work positions[9]
  1. Professor, IISER Kolkata ( 2018 - )
  2. Associate Professor, Indian Institute of Science Education and Research (IISER) Kolkata (2012 - 2015)
  3. Assistant Professor, Indian Institute of Science Education and Research (IISER) Kolkata (2008 - 2012)
  4. Scientist-C, Central Drug Research Institute (CDRI) Lucknow (2005 - 2007)
  5. Post Doctoral Research Associate, University of East Anglia, Norwich, UK (2001 - 2005)

Selected publications

Synthesis of biologically relevant oligosaccharides from plant and bacterial origin
  1. Synthesis of the tetrasaccharide related to the repeating unit of the O-antigen from Azospirillum brasilense Jm125A2 in the form of its 2-aminoethyl glycoside:  Vikramjit Sarkar and Balaram Mukhopadhyay, Carbohydrate Research 2018, 470, 13–18.[10]
  2. Synthesis of Two Hexasaccharides Related to the Repeating Unit of the O-Antigen from Escherichia coli TD2158: Kumar Bhaskar Pal and Balaram Mukhopadhyay, ChemistrySelect 2017, 2, 7378-7381.[11]
  3. Concise synthesis of two trisaccharides related to the saponin isolated from Centratherum anthelminticum: Santanu Mandal and Balaram Mukhopadhyay, Tetrahedron 2007, 63, 11363-11370.[12]
  4. Glycosylated N-sulfonylamidines: Highly efficient copper catalyzed multicomponent reaction with sugar alkynes, sulfonyl azides and amines: Santanu Mandal, Harsh Mohan Gauniyal, Kausikisankar Pramanik, Balaram Mukhopadhyay, Journal of Organic Chemistry 2007, 72, 9753-9756.[13]

Novel methodologies for protecting group manipulations and glycosylation
  1. Sulfuric acid immobilized on silica: an efficient promoter for one-pot acetalation–acetylation of sugar derivatives: Balaram Mukhopadhyay, Tetrahedron Letters 2006, 47, 4337-4341.[14]
  2. H2SO4-silica promoted “on-column” removal of benzylidene, isopropylidene, trityl and tert-butyldimethylsilyl groups: Bimalendu Roy, Priya Verma, Balaram Mukhopadhyay, Carbohydrate Research 2009, 344, 145-148.[15]
  3. A one-pot synthesis of novel sugar derived 5,6-dihydro-quinazolino[4,3-b]quinazolin-8-ones: an entry towards highly functionalized sugar-heterocyclic hybrids: Abhijeet Deb Roy, Arunachalam Subramanian, Balaram Mukhopadhyay, Raja Roy, Tetrahedron Letters 2006, 47, 6857-6860.[16]
  4. Hydrogen bonding-induced conformational change in a crystalline sugar derivative: Kumar Bhaskar Pal, Vikramjit Sarkar and Balaram Mukhopadhyay, Crystal Engineering Communications 2016, 18, 1156-1163[17]

Carbohydrate materials, metal-carbohydrate complexes and glyco nanoparticles
  1. Samarium trifluoromethanesulfonate: an efficient moisture tolerant acylation catalyst under solvent free condition: Bimalendu Roy, Somnath Dasgupta, Vishal Kumar Rajput and Balaram Mukhopadhyay, Journal of Carbohydrate Chemistry 2008, 27, 1-9.[18]
  2. Organoiridium complexes: efficient catalysts for the formation of sugar acetals and ketals: Soumik Mandal, Prashant Ranjan Verma, Balaram Mukhopadhyay, Parna Gupta Carbohydrate Research 2011, 346, 2007-2010.[19]
  3. Phase-selective carbohydrate gelator: Somnath Mukherjee and Balaram Mukhopadhyay RSC Advances 2012, 2(6), 2270 - 2273.[20]
  4. Carbohydrates in Fluoride Sensing: Use of Cyclodextrin and CNC-Based Chemical Probes: Rituparna Das and Balaram Mukhopadhyay, ChemistrySelect, 2017, 2, 4499-4504.[21]

Selected publications
  1. Streamlined Synthesis of Per-O-acetylated Sugars, Glycosyl Iodides or Thioglycosides from Unprotected Sugars, Balaram Mukhopadhyay, K. P. R. Kartha, D. A. Russell and R. A. Field, Journal of Organic Chemistry 2004, 69, 7758-7760.[22]
  2. A one-pot synthesis of novel sugar derived 5,6-dihydro-quinazolino[4,3-b]quinazolin-8-ones: an entry towards highly functionalized sugar-heterocyclic hybrids: Abhijeet Deb Roy, Arunachalam Subramanian, Balaram Mukhopadhyay, Raja Roy, Tetrahedron Letters 2006, 47, 6857-6860.[23]
  3. Glycosylated N-sulfonylamidines: Highly efficient copper catalyzed multicomponent reaction with sugar alkynes, sulfonyl azides and amines: Santanu Mandal, Harsh Mohan Gauniyal, Kausikisankar Pramanik, Balaram Mukhopadhyay, Journal of Organic Chemistry 2007, 72, 9753-9756.[24]
  4. Chemical O-glycosylations: an overview: Rituparna Das and Balaram Mukhopadhyay, ChemistryOPEN 2016, 5, 401-433.[25]
  5. Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists: Vishal Kumar Rajput, Hakon Leffler, Ulf J. Nilsson and Balaram Mukhopadhyay, Bioorganic & Medicinal Chemistry Letters 2014, 24, 3516-3520.[26]

Book chapters
  1. Iodine monobromide - update. R. A. Field and B. Mukhopadhyay in Encyclopedia of Reagents in Organic Synthesis, L. Paquette, P. Fuchs, D. Crich and P. Wipf Eds., John Wiley and Sons Ltd, 2004.[27]
  2. Synthetic Glycans, Glycoarrays, and Glyconanoparticles To Investigate Host Infection by Trypanosoma cruzi Robert A. Field, Peterson Andrade, Vanessa L. Campo, Ivone Carvalho, Beatrice Y. M. Collet, Paul R. Crocker, Margherita Fais, Rositsa Karamanska, Balaram Mukhopadhayay, Sergey A. Nepogodiev, Abdul Rashid, Martin Rejzek, David A. Russell, Claire L. Schofield, and Renate M. van Well, ACS Symposium Series, Chapter 9, 2011, pp 143–159.[28]

Awards
  1. ACCTI Dr. H.C. Srivastava Memorial Award 2017 given by Association of Carbohydrate Chemists and Technologists India (ACCTI).[29]
  2. Excellence in Carbohydrates Reearch Award 2018 given by Association of Carbohydrate Chemists and Technologists India (ACCTI)

References
  1. "Balaram Mukhopadhyay | Ph. D | Indian Institute of Science Education and Research Kolkata, Kolkata | Department of Chemical Sciences | ResearchGate". ResearchGate. Retrieved 2019-07-18.
  2. "Balaram Mukhopadhyay | Ph. D | Indian Institute of Science Education and Research Kolkata, Kolkata | Department of Chemical Sciences | ResearchGate". ResearchGate. Retrieved 2019-07-18.
  3. "Chemistry Tree - Balaram Mukhopadhyay". academictree.org.
  4. "IISER Kolkata - mbalaram". www.iiserkol.ac.in. Retrieved 2019-07-18.
  5. "balaram". balaram. Retrieved 2019-07-18.
  6. "Balaram Mukhopadhyay - Google Scholar Citations". scholar.google.co.in. Retrieved 2019-07-18.
  7. "Balaram Mukhopadhyay". www.journals.elsevier.com. Retrieved 2019-07-18.
  8. "IISER Kolkata - mbalaram". www.iiserkol.ac.in. Retrieved 2019-07-18.
  9. "IISER Kolkata - mbalaram". www.iiserkol.ac.in. Retrieved 2019-07-18.
  10. Sarkar, Vikramjit; Mukhopadhyay, Balaram (December 2018). "Synthesis of the tetrasaccharide related to the repeating unit of the O-antigen from Azospirillum brasilense Jm125A2 in the form of its 2-aminoethyl glycoside". Carbohydrate Research. 470: 13–18. doi:10.1016/j.carres.2018.09.006. PMID 30292926.
  11. Pal, Kumar Bhaskar; Mukhopadhyay, Balaram (2017-08-22). "Synthesis of Two Hexasaccharides Related to the Repeating Unit of the O -Antigen from Escherichia coli TD2158". ChemistrySelect. 2 (24): 7378–7381. doi:10.1002/slct.201701082.
  12. Mandal, Santanu; Mukhopadhyay, Balaram (November 2007). "Concise synthesis of two trisaccharides related to the saponin isolated from Centratherum anthelminticum". Tetrahedron. 63 (46): 11363–11370. doi:10.1016/j.tet.2007.08.077.
  13. Mandal, Santanu; Gauniyal, Harsh Mohan; Pramanik, Kausikisankar; Mukhopadhyay, Balaram (December 2007). "Glycosylated N -Sulfonylamidines: Highly Efficient Copper-Catalyzed Multicomponent Reaction with Sugar Alkynes, Sulfonyl Azides, and Amines †". The Journal of Organic Chemistry. 72 (25): 9753–9756. doi:10.1021/jo701565m. ISSN 0022-3263. PMID 17985923.
  14. Mukhopadhyay, Balaram (June 2006). "Sulfuric acid immobilized on silica: an efficient promoter for one-pot acetalation–acetylation of sugar derivatives". Tetrahedron Letters. 47 (26): 4337–4341. doi:10.1016/j.tetlet.2006.04.118.
  15. Roy, Bimalendu; Verma, Priya; Mukhopadhyay, Balaram (January 2009). "H2SO4-silica-promoted 'on-column' removal of benzylidene, isopropylidene, trityl and tert-butyldimethylsilyl groups". Carbohydrate Research. 344 (1): 145–148. doi:10.1016/j.carres.2008.10.003. PMID 18977476.
  16. Roy, Abhijeet Deb; Subramanian, Arunachalam; Mukhopadhyay, Balaram; Roy, Raja (2007-01-02). "A One-Pot Synthesis of Novel Sugar Derived 5,6-Dihydro-quinazolino[4,3-b]quinazolin-8-ones: An Entry Towards Highly Functionalized Sugar-Heterocyclic Hybrids". ChemInform. 38 (1). doi:10.1002/chin.200701191.
  17. Pal, Kumar Bhaskar; Sarkar, Vikramjit; Mukhopadhyay, Balaram (2016). "Hydrogen bonding-induced conformational change in a crystalline sugar derivative". CrystEngComm. 18 (7): 1156–1163. doi:10.1039/C5CE01893E. ISSN 1466-8033.
  18. Roy, Bimalendu; Dasgupta, Somnath; Kumar Rajput, Vishal; Mukhopadhyay, Balaram (May 2008). "Samarium Trifluoromethanesulfonate: An Efficient Moisture Tolerant Acylation Catalyst under Solvent‐Free Condition". Journal of Carbohydrate Chemistry. 27 (1): 1–9. doi:10.1080/07328300801991245. ISSN 0732-8303.
  19. Mandal, Soumik; Verma, Prashant Ranjan; Mukhopadhyay, Balaram; Gupta, Parna (September 2011). "Organoiridium complexes: efficient catalysts for the formation of sugar acetals and ketals". Carbohydrate Research. 346 (13): 2007–2010. doi:10.1016/j.carres.2011.05.008. PMID 21632036.
  20. Mukherjee, Somnath; Mukhopadhyay, Balaram (2012). "Phase selective carbohydrate gelator". RSC Advances. 2 (6): 2270. doi:10.1039/c2ra00036a. ISSN 2046-2069.
  21. Das, Rituparna; Mukhopadhyay, Balaram (2017-05-31). "Carbohydrates in Fluoride Sensing: Use of Cyclodextrin and CNC-Based Chemical Probes". ChemistrySelect. 2 (16): 4499–4504. doi:10.1002/slct.201700540.
  22. Mukhopadhyay, Balaram; Kartha, K. P. Ravindranathan; Russell, David A.; Field, Robert A. (October 2004). "Streamlined Synthesis of Per- O -acetylated Sugars, Glycosyl Iodides, or Thioglycosides from Unprotected Reducing Sugars 1". The Journal of Organic Chemistry. 69 (22): 7758–7760. doi:10.1021/jo048890e. ISSN 0022-3263. PMID 15498011.
  23. Roy, Abhijeet Deb; Subramanian, Arunachalam; Mukhopadhyay, Balaram; Roy, Raja (2007-01-02). "A One-Pot Synthesis of Novel Sugar Derived 5,6-Dihydro-quinazolino[4,3-b]quinazolin-8-ones: An Entry Towards Highly Functionalized Sugar-Heterocyclic Hybrids". ChemInform. 38 (1). doi:10.1002/chin.200701191.
  24. Mandal, Santanu; Gauniyal, Harsh Mohan; Pramanik, Kausikisankar; Mukhopadhyay, Balaram (December 2007). "Glycosylated N -Sulfonylamidines: Highly Efficient Copper-Catalyzed Multicomponent Reaction with Sugar Alkynes, Sulfonyl Azides, and Amines †". The Journal of Organic Chemistry. 72 (25): 9753–9756. doi:10.1021/jo701565m. ISSN 0022-3263. PMID 17985923.
  25. Das, Rituparna; Mukhopadhyay, Balaram (October 2016). "Chemical O-Glycosylations: An Overview". ChemistryOpen. 5 (5): 401–433. doi:10.1002/open.201600043. PMC 5062006. PMID 27777833.
  26. Rajput, Vishal Kumar; Leffler, Hakon; Nilsson, Ulf J.; Mukhopadhyay, Balaram (August 2014). "Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists". Bioorganic & Medicinal Chemistry Letters. 24 (15): 3516–3520. doi:10.1016/j.bmcl.2014.05.063. PMID 24973029.
  27. "Encyclopedia of Reagents for Organic Synthesis, 14 Volume Set, 2nd Edition". Wiley.com. Retrieved 2019-07-18.
  28. Field, Robert A.; Andrade, Peterson; Campo, Vanessa L.; Carvalho, Ivone; Collet, Beatrice Y. M.; Crocker, Paul R.; Fais, Margherita; Karamanska, Rositsa; Mukhopadhayay, Balaram (January 2011), Huang, Xuefei; Barchi, Joseph J. (eds.), "Synthetic Glycans, Glycoarrays, and Glyconanoparticles To Investigate Host Infection by Trypanosoma cruzi", Petite and Sweet: Glyco-Nanotechnology as a Bridge to New Medicines, American Chemical Society, 1091, pp. 143–159, doi:10.1021/bk-2011-1091.ch009, ISBN 9780841226883
  29. "H. C. Srivastava Young Scientist Award | ACCTI Official Website". Retrieved 2019-07-18.
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