Almokalant

Almokalant is a drug used to treat arrhythmia.[1] It is a potassium channel blocker.[1] It has been found to have teratogenic effects in rats.[2]

Almokalant
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H28N2O3S
Molar mass352.49 g·mol−1
3D model (JSmol)
  (verify)

See also

References

  1. Wiesfeld AC, Crijns HJ, Bergstrand RH, Almgren O, Hillege HL, Lie KI (1993). "Torsades de pointes with Almokalant, a new class III antiarrhythmic drug". American Heart Journal. 126 (4): 1008–1011. doi:10.1016/0002-8703(93)90726-p.
  2. Wellfelt, K.; Sköld, A. C.; Wallin, A.; Danielsson, B. R. (1999-04-01). "Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species". Reproductive Toxicology (Elmsford, N.Y.). 13 (2): 93–101. ISSN 0890-6238. PMID 10213516.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.