ARIH1

Protein ariadne-1 homolog is a protein that in humans is encoded by the ARIH1 gene.[5][6]

ARIH1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesARIH1, ARI, HARI, HHARI, UBCH7BP, ariadne RBR E3 ubiquitin protein ligase 1
External IDsOMIM: 605624 MGI: 1344363 HomoloGene: 111871 GeneCards: ARIH1
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q24.1Start72,474,330 bp[1]
End72,602,987 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

25820

23806

Ensembl

ENSG00000166233

ENSMUSG00000025234

UniProt

Q9Y4X5

Q9Z1K5

RefSeq (mRNA)

NM_005744

NM_019927

RefSeq (protein)

NP_005735

NP_064311

Location (UCSC)Chr 15: 72.47 – 72.6 MbChr 9: 59.39 – 59.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

ARIH1 has been shown to interact with:

References

  1. GRCh38: Ensembl release 89: ENSG00000166233 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025234 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Moynihan TP, Ardley HC, Nuber U, Rose SA, Jones PF, Markham AF, Scheffner M, Robinson PA (November 1999). "The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1". J Biol Chem. 274 (43): 30963–8. doi:10.1074/jbc.274.43.30963. PMID 10521492.
  6. "Entrez Gene: ARIH1 ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)".
  7. Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA (November 2003). "Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP". FEBS Lett. 554 (3): 501–4. doi:10.1016/s0014-5793(03)01235-3. PMID 14623119.
  8. Ardley HC, Tan NG, Rose SA, Markham AF, Robinson PA (June 2001). "Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7". J. Biol. Chem. 276 (22): 19640–7. doi:10.1074/jbc.M011028200. PMID 11278816.

Further reading


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