AKIRIN2

AKIRIN2
Identifiers
Aliases	AKIRIN2, C6orf166, FBI1, dJ486L4.2, akirin 2
External IDs	OMIM: 615165 MGI: 1889364 HomoloGene: 9988 GeneCards: AKIRIN2
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	87,702,233 bp[1]
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)[2]
End	34,566,908 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• enzyme binding; • GO:0001948 protein binding;
Cellular component	• transcriptional repressor complex; • cell nucleus; • nucleoplasm;
Biological process	• multicellular organism development; • positive regulation of endopeptidase activity; • response to lipopolysaccharide; • innate immune system; • negative regulation of transcription, DNA-templated; • regulation of transcription, DNA-templated; • negative regulation of transcription from RNA polymerase II promoter; • negative regulation of gene expression; • transcription, DNA-templated; • positive regulation of cell proliferation; • positive regulation of interleukin-6 production; • positive regulation of transcription from RNA polymerase II promoter; • immune system process; • embryo development ending in birth or egg hatching;
	Sources:Amigo / QuickGO
Orthologs
	55122
	433693
	ENSG00000135334
	ENSMUSG00000028291
	Q53H80
	B1AXD8
	NM_018064
	NM_001007589; NM_026019
	NP_060534
	NP_001007590
	Wikidata
View/Edit Human	View/Edit Mouse

Akirin-2 is a protein that in humans is encoded by the AKIRIN2 gene.[5]

References

Human AKIRIN2 genome location and AKIRIN2 gene details page in the UCSC Genome Browser.

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Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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