AIM1

CRYBG1
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	3CW3, 2DAD,%%s2DAD
Identifiers
Aliases	CRYBG1, ST4, AIM1, absent in melanoma 1, crystallin beta-gamma domain containing 1
External IDs	OMIM: 601797 MGI: 109544 HomoloGene: 18168 GeneCards: CRYBG1
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	106,570,460 bp[1]
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)[2]
End	44,148,853 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• carbohydrate binding; • molecular function;
Cellular component	• cellular component;
Biological process	• biological process;
	Sources:Amigo / QuickGO
Orthologs
	202
	11630
	ENSG00000112297
	ENSMUSG00000019866
	Q9Y4K1; Q96QW7
	n/a
	NM_001624; NM_001371242
	NM_172393; NM_001368305; NM_001368306
	NP_001615; NP_001358171
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Absent in melanoma 1 protein is a protein that in humans is encoded by the AIM1 gene.[5][6][7]

References

GRCh38: Ensembl release 89: ENSG00000112297 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000019866 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Millikin D, Meese E, Vogelstein B, Witkowski C, Trent J (Nov 1991). "Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma". Cancer Research. 51 (20): 5449–53. PMID 1680551.
Rajini B, Graham C, Wistow G, Sharma Y (Apr 2003). "Stability, homodimerization, and calcium-binding properties of a single, variant betagamma-crystallin domain of the protein absent in melanoma 1 (AIM1)". Biochemistry. 42 (15): 4552–9. doi:10.1021/bi027384l. PMID 12693952.
"Entrez Gene: AIM1 absent in melanoma 1".

External links

Human AIM1 genome location and AIM1 gene details page in the UCSC Genome Browser.
PDBe-KB provides an overview of all the structure information available in the PDB for Human Beta/gamma crystallin domain-containing protein 1 (AIM1)

Ray ME, Su YA, Meltzer PS, Trent JM (1996). "Isolation and characterization of genes associated with chromosome-6 mediated tumor suppression in human malignant melanoma". Oncogene. 12 (12): 2527–33. PMID 8700511.
Ray ME, Wistow G, Su YA, et al. (1997). "AIM1, a novel non-lens member of the betagamma-crystallin superfamily, is associated with the control of tumorigenicity in human malignant melanoma". Proceedings of the National Academy of Sciences of the United States of America. 94 (7): 3229–34. doi:10.1073/pnas.94.7.3229. PMC 20351. PMID 9096375.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proceedings of the National Academy of Sciences of the United States of America. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences of the United States of America. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nature Genetics. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Aravind P, Rajini B, Sharma Y, Sankaranarayanan R (2006). "Crystallization and preliminary X-ray crystallographic investigations on a betagamma-crystallin domain of absent in melanoma 1 (AIM1), a protein from Homo sapiens". Acta Crystallographica Section F. 62 (Pt 3): 282–4. doi:10.1107/S1744309106005380. PMC 2197174. PMID 16511323.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112297 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000019866 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1680551-5] Millikin D, Meese E, Vogelstein B, Witkowski C, Trent J (Nov 1991). "Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma". Cancer Research. 51 (20): 5449–53. PMID 1680551.

[pmid12693952-6] Rajini B, Graham C, Wistow G, Sharma Y (Apr 2003). "Stability, homodimerization, and calcium-binding properties of a single, variant betagamma-crystallin domain of the protein absent in melanoma 1 (AIM1)". Biochemistry. 42 (15): 4552–9. doi:10.1021/bi027384l. PMID 12693952.

[entrez-7] "Entrez Gene: AIM1 absent in melanoma 1".

AIM1

References

External links

Further reading