8-Bromoguanosine 3',5'-cyclic monophosphate

8-Bromoguanosine 3',5'-cyclic monophosphate is a brominated derivative of cyclic guanosine monophosphate (cGMP).[1] It acts as an activator of cGMP-dependent protein kinases.[2]

8-Bromoguanosine 3',5'-cyclic monophosphate
Names
IUPAC name
2-amino-8-bromo-9-[(1S,6R,8R,9R)-3,9-dihydroxy-3-oxo-2,4,7-trioxa-3λ5-phosphabicyclo[4.3.0]nonan-8-yl]-3H-purin-6-one
Other names
8-Bromocyclic GMP;8-Bromo-cGMP; 8-Br-cyclic GMP; 8-Br-cGMP
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
Properties
C10H11BrN5O7P
Molar mass 424.104 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

See also

References

  1. Rapoport, RM; Draznin, MB; Murad, F (Nov 1982). "Sodium nitroprusside-induced protein phosphorylation in intact rat aorta is mimicked by 8-bromo cyclic GMP" (Free full text). Proceedings of the National Academy of Sciences of the United States of America. 79 (21): 6470–4. doi:10.1073/pnas.79.21.6470. ISSN 0027-8424. PMC 347148. PMID 6292902.
  2. 8-Bromoguanosine-3',5'-cyclic monophosphate ( 8-Br-cGMP )
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.