2019 US Open – Wheelchair Women's Singles
Diede de Groot was the defending champion and successfully defended her Wheelchair Women's Singles tennis title at the 2019 US Open, defeating Yui Kamiji in the final, 4–6, 6–1, 6–4.
| Wheelchair Women's Singles | |
|---|---|
| 2019 US Open | |
| Champion |  |
| Runner-up |  |
| Final score | 4–6, 6–1, 6–4 |
Seeds
Draw
Key
- Q = Qualifier
- WC = Wild Card
- LL = Lucky Loser
- Alt = Alternate
- SE = Special Exempt
- PR = Protected Ranking
- ITF = ITF entry
- JE = Junior Exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
Finals
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | | 6 | 6 | |||||||||||||||||
 | 1 | 0 | ||||||||||||||||||
| 1 | | 6 | 6 | |||||||||||||||||
| WC |  | 3 | 2 | |||||||||||||||||
 | 3 | 6 | 1 | |||||||||||||||||
| WC | | 6 | 0 | 6 | ||||||||||||||||
| 1 | | 4 | 6 | 6 | ||||||||||||||||
| 2 | | 6 | 1 | 4 | ||||||||||||||||
| 6 | 6 | ||||||||||||||||||
 | 1 | 4 | ||||||||||||||||||
| 1 | 3 | ||||||||||||||||||
| 2 | | 6 | 6 | |||||||||||||||||
| 1 | 3 | ||||||||||||||||||
| 2 | | 6 | 6 | |||||||||||||||||
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