2-(Ethylamino)-1,2-diphenylethanone

2-(Ethylamino)-1,2-diphenylethanone
Clinical data
ATC code	None;
Identifiers
	IUPAC name 2-(ethylamino)-1,2-diphenylethanone;
CAS Number	22312-16-9 ;
PubChem CID	69702363;
Chemical and physical data
Formula	C16H17NO
Molar mass	239.318 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCNC(C1=CC=CC=C1)C(=O)C2=CC=CC=C2;
	InChI InChI=1S/C16H17NO/c1-2-17-15(13-9-5-3-6-10-13)16(18)14-11-7-4-8-12-14/h3-12,15,17H,2H2,1H3; Key:NHNVMSYWZNJBOO-UHFFFAOYSA-N;

2-(Ethylamino)-1,2-diphenylethanone (also known as α-ethylamino-deoxybenzoin, [α-(Ethylamino)benzyl]-(phenyl)-ketone and βk-Ephenidine) is a chemical compound which was first invented in 1955,[1] researched by ICI in 1969 as an antidepressant,[2] and subsequently claimed by AstraZeneca as an inhibitor of the enzyme 11β-Hydroxysteroid dehydrogenase type 1.[3] No other pharmacological data has been disclosed, though its chemical structure closely resembles that of certain designer drug compounds such as ephenidine and N-ethylhexedrone.

References

Hinderling R, Prijs B, Erlenmeyer H. Über α‐Alkylamino‐ketone. Helvetica Chimica Acta 1955; 38(6):1415-1420. doi:10.1002/hlca.19550380613
Gilman DJ. Desyl amines and compositions thereof. Patent GB 1143263, 1969.
Barton P, et al. Ketones. Patent US 2005/0272036

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[1] Hinderling R, Prijs B, Erlenmeyer H. Über α‐Alkylamino‐ketone. Helvetica Chimica Acta 1955; 38(6):1415-1420. doi:10.1002/hlca.19550380613

[2] Gilman DJ. Desyl amines and compositions thereof. Patent GB 1143263, 1969.

[3] Barton P, et al. Ketones. Patent US 2005/0272036

2-(Ethylamino)-1,2-diphenylethanone

See also

References