NDC1

NDC1
Identifiers
AliasesNDC1, NET3, TMEM48, NDC1 transmembrane nucleoporin
External IDsMGI: 1920037 HomoloGene: 41224 GeneCards: NDC1
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p32.3Start53,765,460 bp[1]
End53,838,860 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55706

72787

Ensembl

ENSG00000058804

ENSMUSG00000028614

UniProt

Q9BTX1

Q8VCB1

RefSeq (mRNA)

NM_001168551
NM_018087

NM_028355

RefSeq (protein)

NP_001162023
NP_060557

NP_082631

Location (UCSC)Chr 1: 53.77 – 53.84 MbChr 4: 107.37 – 107.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nucleoporin NDC1 is a protein that in humans is encoded by the TMEM48 gene.[5][6][7] It anchors aladin to the nuclear pore complex.[8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000058804 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028614 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Lau CK, Delmar VA, Forbes DJ (Aug 2006). "Topology of yeast Ndc1p: predictions for the human NDC1/NET3 homologue". Anat Rec A Discov Mol Cell Evol Biol. 288 (7): 681–94. doi:10.1002/ar.a.20335. PMC 3049984. PMID 16779818.
  6. ↑ Schirmer EC, Florens L, Guan T, Yates JR 3rd, Gerace L (Sep 2003). "Nuclear membrane proteins with potential disease links found by subtractive proteomics". Science. 301 (5638): 1380–2. doi:10.1126/science.1088176. PMID 12958361.
  7. ↑ "Entrez Gene: TMEM48 transmembrane protein 48".
  8. ↑ Kind, Barbara; Koehler, Katrin; Lorenz, Mike; Huebner, Angela (December 2009). "The nuclear pore complex protein ALADIN is anchored via NDC1 but not via POM121 and GP210 in the nuclear envelope". Biochemical and Biophysical Research Communications. 390 (2): 205–210. doi:10.1016/j.bbrc.2009.09.080.

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
  • Mansfeld J, Güttinger S, Hawryluk-Gara LA, et al. (2006). "The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells". Mol. Cell. 22 (1): 93–103. doi:10.1016/j.molcel.2006.02.015. PMID 16600873.
  • Stavru F, Hülsmann BB, Spang A, et al. (2006). "NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes". J. Cell Biol. 173 (4): 509–19. doi:10.1083/jcb.200601001. PMC 2063861. PMID 16702233.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.


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