Salvinorin

Salvinorins are a group of natural chemical compounds and their structural analogs. Several salvinorins have been isolated from Salvia divinorum. They are classified as diterpenoid furanolactones. Salvinorin A is a hallucinogen with dissociative effects.

Several salvinorins have been isolated and characterized.

Natural salvinorins
NameStructureR1R2Chemical formulaMolar massCAS numberPubChem
Salvinorin A
–OCOCH3C23H28O8432.46 g·mol−183729-01-5CID 128563 from PubChem
Salvinorin B–OHC21H26O7390.43 g·mol−192545-30-7CID 11440685 from PubChem
Salvinorin C
–OCOCH3–OCOCH3C25H30O9475.29 g·mol−1385785-99-9
Salvinorin D–OCOCH3–OHC23H28O8432.47 g·mol−1540770-13-6
Salvinorin E–OH–OCOCH3C23H28O8432.47 g·mol−1540770-14-7
Salvinorin F–OH–HC21H26O6374.43 g·mol−1540770-15-8
Salvinorin G=O–OCOCH3C23H26O8430.45 g·mol−1866622-54-0
Salvinorin H–OH–OHC21H26O7390.43 g·mol−1872004-62-1
Salvinorin I
C21H28O7392.45 g·mol−1917951-71-4
17α-Salvinorin JC23H30O8434.49 g·mol−11157894-83-1
17β-Salvinorin JC23H30O8434.49 g·mol−11157894-85-3

Analogs

Because of their biological activities, synthetic and semi-synthetic analogs have been prepared for study. Semi-synthetic analogs include salvinorin B ethoxymethyl ether and salvinorin B methoxymethyl ether. Fully synthetic analogs include herkinorin.

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