SETD3 (gene)

SETD3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3SMT
Identifiers
Aliases	SETD3, C14orf154, SET domain containing 3
External IDs	MGI: 1289184 HomoloGene: 41748 GeneCards: SETD3
Gene location (Human)
Chr.	Chromosome 14 (human)[1]
End	99,480,889 bp[1]
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)[2]
End	108,179,314 bp[2]
Gene ontology
Molecular function	• methyltransferase activity; • transferase activity; • RNA polymerase II activating transcription factor binding; • histone methyltransferase activity (H3-K4 specific); • histone-lysine N-methyltransferase activity; • histone methyltransferase activity (H3-K36 specific); • transcription coactivator activity; • protein-lysine N-methyltransferase activity;
Cellular component	• nucleoplasm; • cell nucleus; • nuclear chromatin;
Biological process	• regulation of transcription, DNA-templated; • positive regulation of muscle cell differentiation; • transcription, DNA-templated; • positive regulation of transcription, DNA-templated; • peptidyl-lysine methylation; • methylation; • positive regulation of transcription from RNA polymerase II promoter; • peptidyl-lysine dimethylation; • peptidyl-lysine trimethylation; • histone H3-K36 methylation; • peptidyl-lysine monomethylation; • histone H3-K4 methylation; • chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	84193
	52690
	ENSG00000183576
	ENSMUSG00000056770
	Q86TU7
	Q91WC0
	NM_032233; NM_199123
NM_028262; NM_001364266; NM_001364267; NM_001364268; NM_001364269;
	NM_001364270
	NP_115609; NP_954574
NP_082538; NP_001351195; NP_001351196; NP_001351197; NP_001351198;
	NP_001351199
	Wikidata
View/Edit Human	View/Edit Mouse

SET domain containing 3 (SETD3) is a protein that in humans is encoded by the SETD3 gene. ^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000183576 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000056770 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: SET domain containing 3". Retrieved 2018-01-22.

Cooper SE, Hodimont E, Green CM (2015). "A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells". Cell Cycle. 14 (15): 2509–19. doi:10.1080/15384101.2015.1053667. PMC 4613188. PMID 26030842.
Pires-Luís AS, Vieira-Coimbra M, Vieira FQ, Costa-Pinheiro P, Silva-Santos R, Dias PC, Antunes L, Lobo F, Oliveira J, Gonçalves CS, Costa BM, Henrique R, Jerónimo C (2015). "Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication". Epigenetics. 10 (11): 1033–43. doi:10.1080/15592294.2015.1103578. PMC 4844211. PMID 26488939.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000183576 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000056770 - Ensembl, May 2017

[3] "Human PubMed Reference:".

[4] "Mouse PubMed Reference:".

[entrez-5] "Entrez Gene: SET domain containing 3". Retrieved 2018-01-22.

SETD3 (gene)

See also

References

Further reading