Pharmacological body alteration

Pharmacological body alteration is the overt physical alteration of the body through the use of drugs. Examples include the following:

• The use of anabolic steroids in bodybuilders to increase muscle mass and strength
• The use of growth hormone and insulin-like growth factor 1 to increase height and body size in short stature, growth hormone deficiency, and Laron syndrome
• The use of hormonal breast enhancement to increase breast size in women, hormonal clitoris enlargement to increase clitoris size in women, and hormonal penis enlargement to increase penis size in men
• The use of hormone replacement therapy in transgender and intersex people and people with sex hormone imbalances (e.g., hypogonadism or hyperandrogenism) to change the secondary sexual characteristics from masculine to feminine and vice versa

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