Nucleoporin 160

NUP160
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUP160, nucleoporin 160, Nup160, 160kDa, 2810011M03Rik, AA414952, AU020188, Gtl-13, Gtl1-13, Gtl13, mKIAA0197
External IDsMGI: 1926227 HomoloGene: 32509 GeneCards: NUP160
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p11.2Start47,778,087 bp[1]
End47,848,555 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23279

59015

Ensembl

ENSG00000030066
ENSG00000285358

ENSMUSG00000051329

UniProt

Q12769

Q9Z0W3

RefSeq (mRNA)

NM_015231
NM_001318399

NM_021512

RefSeq (protein)

NP_001305328
NP_056046

NP_067487

Location (UCSC)Chr 11: 47.78 – 47.85 MbChr 2: 90.68 – 90.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nucleoporin 160 (Nup160) is a protein that in humans is encoded by the NUP160 gene.[5][6]

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM][6]

References

  1. 1 2 3 ENSG00000285358 GRCh38: Ensembl release 89: ENSG00000030066, ENSG00000285358 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051329 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Vasu S, Shah S, Orjalo A, Park M, Fischer WH, Forbes DJ (Oct 2001). "Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export". J Cell Biol. 155 (3): 339–54. doi:10.1083/jcb.200108007. PMC 2150853. PMID 11684705.
  6. 1 2 "Entrez Gene: NUP160 nucleoporin 160kDa".

Further reading

  • Nagase T, Seki N, Ishikawa K, et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.
  • Belgareh N, Rabut G, Baï SW, et al. (2001). "An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells". J. Cell Biol. 154 (6): 1147–60. doi:10.1083/jcb.200101081. PMC 2150808. PMID 11564755.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Loïodice I, Alves A, Rabut G, et al. (2005). "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Mol. Biol. Cell. 15 (7): 3333–44. doi:10.1091/mbc.E03-12-0878. PMC 452587. PMID 15146057.
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
  • Orjalo AV, Arnaoutov A, Shen Z, et al. (2006). "The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly". Mol. Biol. Cell. 17 (9): 3806–18. doi:10.1091/mbc.E05-11-1061. PMC 1593160. PMID 16807356.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  • Glavy JS, Krutchinsky AN, Cristea IM, et al. (2007). "Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex". Proc. Natl. Acad. Sci. U.S.A. 104 (10): 3811–6. doi:10.1073/pnas.0700058104. PMC 1820666. PMID 17360435.
  • Zuccolo M, Alves A, Galy V, et al. (2007). "The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions". EMBO J. 26 (7): 1853–64. doi:10.1038/sj.emboj.7601642. PMC 1847668. PMID 17363900.


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