INT (chemical)

INT
Names
IUPAC name
3-(4-Iodophenyl)-2-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium chloride
Other names
2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.005.161
Properties
C19H13ClIN5O2
Molar mass 505.70 g·mol−1
Melting point 240 °C (464 °F; 513 K) (decomposes)
Solubility in methanol: water (1:1) 50 mg/mL hot, very faintly turbid, very deep yellow
log P −2.4
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

INT or 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium is a popularly-used tetrazolium salt (usually prepared with chloride ions), similar to tetrazolium chloride that on reduction produces a red formazan dye that can be used for quantitative redox assays. It is also toxic to prokaryotes.[1]

See also

References

  1. Villegas-Mendoza, Josué; Cajal-Medrano, Ramón; Maske, Helmut (2015). "INT (2-(4-Iodophenyl)-3-(4-Nitrophenyl)-5-(Phenyl) Tetrazolium Chloride) Is Toxic to Prokaryote Cells Precluding Its Use with Whole Cells as a Proxy for In Vivo Respiration". Microbial Ecology. 70 (4): 1004–1011. doi:10.1007/s00248-015-0626-3. PMID 25991603.


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