DHRS7

DHRS7
Identifiers
AliasesDHRS7, SDR34C1, retDSR4, retSDR4, CGI-86, dehydrogenase/reductase (SDR family) member 7, dehydrogenase/reductase 7
External IDsMGI: 1913625 HomoloGene: 9350 GeneCards: DHRS7
Gene location (Human)
Chr.Chromosome 14 (human)[1]
Band14q23.1Start60,144,120 bp[1]
End60,169,856 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

51635

66375

Ensembl

ENSG00000100612

ENSMUSG00000021094

UniProt

Q9Y394

Q9CXR1

RefSeq (mRNA)

NM_016029
NM_001322280
NM_001322281
NM_001322282

NM_025522

RefSeq (protein)

NP_001309209
NP_001309210
NP_001309211
NP_057113

NP_079798

Location (UCSC)Chr 14: 60.14 – 60.17 MbChr 12: 72.65 – 72.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dehydrogenase/reductase (SDR family) member 7 is a protein that in humans is encoded by the DHRS7 gene.[5]

Function

Short-chain dehydrogenases/reductases (SDRs), such as DHRS7, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000100612 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021094 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. "Entrez Gene: Dehydrogenase/reductase (SDR family) member 7". Retrieved 2014-04-28.
  6. Haeseleer F, Palczewski K (2000). "Short-chain dehydrogenases/reductases in retina". Methods in Enzymology. Methods in Enzymology. 316: 372–83. doi:10.1016/S0076-6879(00)16736-9. ISBN 9780121822170. PMID 10800688.

Further reading

  • Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jörnvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (March 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chemico-Biological Interactions. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
  • Ramasamy A, Curjuric I, Coin LJ, Kumar A, McArdle WL, Imboden M, Leynaert B, Kogevinas M, Schmid-Grendelmeier P, Pekkanen J, Wjst M, Bircher AJ, Sovio U, Rochat T, Hartikainen AL, Balding DJ, Jarvelin MR, Probst-Hensch N, Strachan DP, Jarvis DL (November 2011). "A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order". The Journal of Allergy and Clinical Immunology. 128 (5): 996–1005. doi:10.1016/j.jaci.2011.08.030. PMID 22036096.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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