Chris Sander (scientist)

Chris Sander
Chris Sander speaking at ISMB in 2010
Born Germany
Alma mater University of Berlin
University of California, Berkeley[1]
Known for Bioinformatics
Computational biology
Cancer genomics[2]
Awards
Scientific career
Institutions Dana Farber Cancer Institute
Memorial Sloan–Kettering Cancer Center
Rockefeller University
Cornell University
Weizmann Institute of Science[4]
Thesis Analytic properties of bound state wave functions (1975)
Doctoral students Burkhard Rost
Website www.mskcc.org/research/lab/chris-sander

Chris Sander is a computational biologist and chair of the Computational Biology Programme at the Memorial Sloan–Kettering Cancer Center in New York City.[5][6][7][8][9][10][11] Recently, he moved his lab to the DFCI at Harvard.

Education

Sander originally trained as a physicist receiving his undergraduate degree from the University of Berlin in 1967.[1] After a period studying at the University of California, Berkeley and the Niels Bohr Institute in Copenhagen,[1][12] he gained his PhD degree in theoretical physics from the State University of New York in 1975. His thesis was titled Analytic properties of bound state wave functions.[13]

Research

Sander credits his move from theoretical physics to computational biology to Fred Sanger's 1977 landmark paper in Nature,[14] in which the nucleotide sequence of bacteriophage φX174 was published.[1] Sander has made many contributions to the field of structural bioinformatics including developing tools such as the Families of Structurally Similar Proteins (FSSP) database[15] and the DSSP algorithm for assigning secondary structure to the amino acids of a protein, given the atomic-resolution coordinates of that protein.[16]

Sander has also worked at the European Bioinformatics Institute, has served as chief information officer for the biopharmaceutical company Millennium Pharmaceuticals and has been an advisor to IBM's Deep Computing Initiative, which produced the Deep Blue chess computer.[17]

Roles and Honours

Sander is a former Executive Editor for the journal Bioinformatics. In 2014 he was appointed one of the first Honorary Editors of Bioinformatics.[18]

Sander was awarded the ISCB Accomplishment by a Senior Scientist Award in 2010.[12] He was awarded the 2018 DeLano Award for Computational Biosciences.[19]

Personal life

Sander is the brother of German actor Otto Sander.[20]

References

  1. 1 2 3 4 "At Work: Computational Biology Program Chair Chris Sander | Memorial Sloan-Kettering Cancer Center". Archived from the original on 2013-08-20.
  2. ↑ Holm, L.; Sander, C. (1993). "Protein Structure Comparison by Alignment of Distance Matrices". Journal of Molecular Biology. 233 (1): 123–138. doi:10.1006/jmbi.1993.1489. PMID 8377180.
  3. ↑ McKay, B. M.; Sansom, C. (2010). "2010 ISCB Overton Prize Awarded to Steven E. Brenner". PLoS Computational Biology. 6 (6): e1000831. doi:10.1371/journal.pcbi.1000831. PMC 2891695. PMID 20585610.
  4. ↑ Lifson, Shneior; Sander, Christian (1979). "Antiparallel and parallel β-strands differ in amino acid residue preferences". Nature. 282 (5734): 109–111. doi:10.1038/282109a0. PMID 503185.
  5. ↑ Chris Sander at DBLP Bibliography Server Edit this at Wikidata
  6. ↑ Chris Sander publications indexed by Google Scholar Edit this at Wikidata
  7. ↑ List of publications from Microsoft Academic
  8. ↑ Sander, Chris A.'s publications indexed by the Scopus bibliographic database. (subscription required)
  9. ↑ John, B.; Enright, A. J.; Aravin, A.; Tuschl, T.; Sander, C.; Marks, D. S. (2004). "Human MicroRNA Targets". PLoS Biology. 2 (11): e363. doi:10.1371/journal.pbio.0020363. PMC 521178. PMID 15502875.
  10. ↑ Rost, B.; Sander, C. (1993). "Prediction of Protein Secondary Structure at Better than 70% Accuracy". Journal of Molecular Biology. 232 (2): 584–599. doi:10.1006/jmbi.1993.1413. PMID 8345525.
  11. ↑ Sander, C.; Schulz, G. E. (1979). "Degeneracy of the information contained in amino acid sequences: Evidence from overlaid genes". Journal of Molecular Evolution. 13 (3): 245–252. doi:10.1007/BF01739483. PMID 228047.
  12. 1 2 http://www.iscb.org/iscb-awards/1133
  13. ↑ "INIS Collection Search - Single Result". Retrieved 13 August 2015.
  14. ↑ Sanger, F.; Air, G. M.; Barrell, B. G.; Brown, N. L.; Coulson, A. R.; Fiddes, J. C.; Hutchison, C. A.; Slocombe, P. M.; Smith, M. (24 February 1977). "Nucleotide sequence of bacteriophage φX174 DNA". Nature. 265 (5596): 687–695. doi:10.1038/265687a0. PMID 870828.
  15. ↑ Holm L, Ouzounis C, Sander C, Tuparev G, Vriend G (1992). "A database of protein structure families with common folding motifs". Protein Science. 1 (12): 1691–1698. doi:10.1002/pro.5560011217. PMC 2142138. PMID 1304898.
  16. ↑ Kabsch, W.; Sander, C. (1983). "Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features". Biopolymers. 22 (12): 2577–2637. doi:10.1002/bip.360221211. PMID 6667333.
  17. ↑ "Bio-IT World: Horizons - Chris Sander". Retrieved 13 August 2015.
  18. ↑ "15 years of "Bioinformatics"". Bioinformatics. 30 (6): 747. 2014. doi:10.1093/bioinformatics/btu076. PMID 24642573.
  19. ↑ "DeLano Award for Computational Biosciences". www.asbmb.org. Retrieved 15 September 2017.
  20. ↑ Biography for Otto Sander on IMDb
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