Chih-Ming Ho

Dr. Chih-Ming Ho (Chinese: 何志明（Pinyin: Hé Zhìmíng) is a Distinguished Research Professor at UCLA's Henry Samueli School of Engineering and Applied Science.

Honors

• Member: US National Academy of Engineering
• Academician: Academia Sinica
• Doctor of Engineering Honoris Causa: Hong Kong University of Science and Technology
• Fellow: The American Association for the Advancement of Science (AAAS)
• Fellow: American Institute of Medical and Biological Engineering (AIMBE)
• Fellow: American Physical Society (APS)
• Fellow: American Institute of Aeronautics and Astronautics (AIAA)
• Fellow: International Society for Nano Manipulation, Manufacturing and Measurement (3M-Nano)

Awards

• Distinguished Alumnus of National Taiwan University
• Global Achievement Award: The Johns Hopkins University
• The Johns Hopkins University Society of Scholars
• UCLA-Allied Signal Faculty Research Award

Honorary Professorship

• Ben Rich - Lockheed Martin Professor
• Einstein Professor, Chinese Academy of Sciences
• K. T. Lee Honorary Chair Professor of National Cheng Kung University
• Honorary Research Professor of National Taiwan University
• Kuo-Nien Honorary Professor of National Tsinghua University
• Honorary Chair Professor of National Chao-Tung University
• Honorary Chair Professor of National Tsinghua University
• Honorary Professor of Institute of Mechanics, Chinese Academy of Sciences
• Honorary Professor of Nanjing University of Aeronautics and Astronautics

Research and selected publications

Dr. Ho is known for his work in micro/nano fluidics, bio-nano technologies and turbulence. He has published 260 papers and is ranked by ISI as one of the top 250 most cited researchers worldwide in the entire engineering category. He has delivered 18 named distinguished lectures and presented over 130 keynote talks at international conferences.

• Ho, C.M. and Nosseir, N.S.M., "Dynamics of an Impinging Jet: Part 1; The Feedback Mechanism", Journal of Fluid Mechanics, Vol. 105, pp. 119–142, 1981.
• Ho, C.M. and Huang, L.S., "Subharmonics and Vortex Merging in Mixing Layers", Journal of Fluid Mechanics, Vol. 119, pp. 443–473, 1982.
• Ho, C.M. and Huerre, P., "Perturbed Free Shear Layers," Annu. Rev. of Fluid Mech., Vol. 16, pp. 365–424, 1984.
• Didden, N. and Ho, C.M., "Unsteady Separation in a Boundary Layer Produced by an Impinging Jet", Journal of Fluid Mechanics, Vol. 160, pp. 235–256, 1985.
• Ho, C.M. and Gutmark, E., "Vortex Induction and Mass Entrainment in a Small Aspect Ratio Elliptic Jet", Journal of Fluid Mechanics, Vol. 179, pp. 383–405, 1987.
• Ho, C. M. and Tai Y.C., "Micro-Electro-Mechanical-Systems and Fluid Flows", Annu. Rev. of Fluid Mech., vol. 30, pp. 579–612, 1998.
• Gau, J.J., Lan, E. H., Dunn, B., Ho, C.M., "A MEMS-based Amperometric Detector for E. Coli Bacteria - Using Self-Assembled Monolayers", Journal of Biosensor and Bioelectronics, Volume 9, Number 12, pp. 745–755, 2001.
• Huang, J., Liu, M., Knight, L. D., Grody, W. W. Miller, J. F., and Ho, C. M., "An Electrochemical Detection Scheme for Identifications of Single-Nucleotide Polymorphism Using Hairpin-forming Probes", Nucleic Acids Research, Vol.30, No.12, e55, 2002.
• Tseng, F.G., Kim, C.J. and Ho, C.M., "A High Resolution High Frequency Monolithic Microinjector Ejecting Picoliter Droplets Free of Satellite Drops: Part I Concept, Design and Model, Part II, Fabrication, Implementation and Characterization", JMEMS, 11(5): 427-447, October 2002.
• Huang, T. J., Tseng, H.R., Sha, L., Lu, W., Brough, B., Flood, A.H., Yu, B.D., Celestre, P.C., Chang, J. P., Stoddart, J. F., and Ho, C.M., "Mechanical Shuttling of Linear Motor-Molecules in Condensed Phases on Solid Substrates", Nano Letters, 4(11):2065-2071, 2004.
• Huang, T. J., Liu, Y., Brough, B., Flood, A.H., Bonvallet, P., Tseng, H.R., Baller, M., Magonov, S., Stoddart, J.F. and Ho, C.M., "A Nanomechanical Device Based on Linear Molecular Motors", Applied Physics Letters, Vol. 85, Issue 22, 5391-5393, 2004.
• Wang, T.H., Peng, Y., Zhang, C., Wong, P.K. and Ho, C.M., "Single-Molecule Tracing on a Fluidic Microchip for Quantitative Detection of Low-Abundance Nucleic Acids",Journal of the American Chemical Society 127, 5354-5359, 2005.
• Cubaud, T., Tatineni, M., Zhong, X., and Ho, C.M., "Bubble Dispenser in Microfluidic Devices", Physical Review E 72, 037302, 2005.
• Brough B., Northrop B., Schmidt J., Tseng, H., Houk K., Stoddart F., Ho, C. M., "Evaluation of Synthetic Linear Motor-Molecule Actuation Energetics", Proceedings of National Academy of Sciences, vol. 103, pp. 8583–8588, 2006.
• Lee, Y.-K., Shih, C., Tabeling, P. and Ho, C.M., "Experimental study and nonlinear dynamic analysis of time-periodic micro chaotic mixers", J. Fluid Mech. Vol. 575, pp. 425–448, 2007.
• Wong, P.K, Yu, F., Shahangian A., Cheng, G., Sun, R. and Ho, C.M., "Closed-Loop Control of Cellular Functions Using Combinatory Drugs Guided by a Stochastic Search Algorithm", Proceeding of National Academy of Science, Vol. 105, no.13 pp. 5105–5110, 2008.
• Wei, F., Wang, J., Liao, W., Zimmermann, B.G., Wong, D.T. and Ho, C.M., "Electrochemical Detection of Low-Copy Number Salivary RNA based on Specific Signal Amplification with a Hairpin Probe", doi:10.1093/nar/gkn299, Nucleic Acids Research Vol. 36 No.11, P. e 65, 2008.
• Li, N. and Ho, C.M., "Aptamer-Based Optical Probes with Separated Molecular Recognition and Signal Transduction Modules", Journal of American Chemical Society, Vol. 130, pp. 2380–2381, 2008.
• Sun, C.P., Usui, T., Yu, F., Al-Shyoukh, I., Shamma, J., Sun, R., and Ho, C.M., "Integrative Systems Control Approach for Reactivating Kaposi’s Sarcoma-associated herpesvirus (KSHV) with Combinatory Drugs", Integr. Biol., 1, 123-130, 2009.
• Wong, T.S., Huang, P.H. and Ho, C.M., "Wetting Behaviors of Individual Nanostructures", Langmuir, Vol. 25, No. 12, pp. 6599 – 6603, 2009
• Tsutsui, H., Valamehr, B., Hindoyan, A., Qiao, R., Ding, X., Guo, S., Witte, O.N., Liu, X., Ho, C.M., and Wu, H., "An Optimized Small Molecule Inhibitor Cocktail Supports Long- term Maintenance of Human Embryonic Stem Cells", Nature Communications, 2:167, 2011.
• Al-Shyoukh, I., Yu, F., Feng, J., Yan, K., Dubinett, S., Ho, C. M., Shamma, J.S. and Sun R., "Systematic quantitative characterization of cellular responses induced by multiple signals, BMC Systems Biology, Vol. 5, pp. 88, 2011
• Chen, T.H., Hsu, J. J., Zhao, X., Guo, C., Wong, M.N., Huang, Y., Li, Z. W., Garfinkel, A., Ho, C.M., Tintut, Y., and Demer, L.L., "Left-Right Symmetry Breaking in Tissue Morphogenesis via Cytoskeletal Mechanics", Circulations Research, vol.110, pp. 551–559, 2012.
• Ding, X. T., Sanchez, D. J., Shahangian, A., Al-Shyoukh, I., Cheng, G., and Ho, C. M., "Cascade Search for HSV-1 Combinatorial Drugs with High Antiviral Efficacy and Low Toxicity", International Journal of Nanomedicine, Vol. 7, 2281-2292, 2012.

References

External links

• Ho Lab Personalized Medicine
• UCLA MAE Chih-Ming Ho