NREP

NREP
Identifiers
Aliases	NREP, C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17, neuronal regeneration related protein
External IDs	MGI: 99444 HomoloGene: 70874 GeneCards: NREP
Gene location (Human)
Chr.	Chromosome 5 (human)[1]
End	111,997,464 bp[1]
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)[2]
End	33,464,029 bp[2]
RNA expression pattern
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	• protein binding;
Cellular component	• cytoplasm; • cell nucleus;
Biological process	• regulation of neuron differentiation; • axon regeneration; • regulation of transforming growth factor beta receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9315
	27528
	ENSG00000134986
	ENSMUSG00000042834
	Q16612
	Q07475
NM_001142474; NM_001142475; NM_001142476; NM_001142477; NM_001142478;
	NM_001142479; NM_001142480; NM_001142481; NM_001142482; NM_001142483; NM_004772
	NM_001109988; NM_001109989; NM_001267717; NM_053078
NP_001135946; NP_001135947; NP_001135948; NP_001135949; NP_001135950;
	NP_001135951; NP_001135952; NP_001135953; NP_001135954; NP_001135955; NP_004763
	NP_001103458; NP_001103459; NP_001254646; NP_444308
	Wikidata
View/Edit Human	View/Edit Mouse

Neuronal protein 3.1 is a protein that in humans is encoded by the NREP gene.^[5]^[6]^[7] It is highly expressed in the brain.^[8]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000134986 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042834 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Studler JM, Glowinski J, Lévi-Strauss M (Jun 1993). "An abundant mRNA of the embryonic brain persists at a high level in cerebellum, hippocampus and olfactory bulb during adulthood". The European Journal of Neuroscience. 5 (6): 614–23. doi:10.1111/j.1460-9568.1993.tb00527.x. PMID 8261136.
↑ Miura N, Naganuma A (Aug 2000). "Metallothionein mediates gene expression of 3.1 mRNA (PTZ17) related to epileptic seizure". FEBS Letters. 479 (3): 146–8. doi:10.1016/S0014-5793(00)01899-8. PMID 10981724.
↑ "Entrez Gene: C5orf13 chromosome 5 open reading frame 13".
↑ "Human Gene NREP (ENST00000447165.6) Description and Page Index". genome.ucsc.edu.

Human NREP genome location and NREP gene details page in the UCSC Genome Browser.

Taylor GA, Hudson E, Resau JH, Vande Woude GF (Feb 2000). "Regulation of P311 expression by Met-hepatocyte growth factor/scatter factor and the ubiquitin/proteasome system". The Journal of Biological Chemistry. 275 (6): 4215–9. doi:10.1074/jbc.275.6.4215. PMID 10660586.
Pan D, Zhe X, Jakkaraju S, Taylor GA, Schuger L (Nov 2002). "P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype". The Journal of Clinical Investigation. 110 (9): 1349–58. doi:10.1172/JCI15614. PMC 151607. PMID 12417574.
McDonough WS, Tran NL, Berens ME (Sep 2005). "Regulation of glioma cell migration by serine-phosphorylated P311". Neoplasia. 7 (9): 862–72. doi:10.1593/neo.05190. PMC 1501936. PMID 16229809.
Zhao L, Leung JK, Yamamoto H, Goswami S, Kheradmand F, Vu TH (Jul 2006). "Identification of P311 as a potential gene regulating alveolar generation". American Journal of Respiratory Cell and Molecular Biology. 35 (1): 48–54. doi:10.1165/rcmb.2005-0475OC. PMC 2658697. PMID 16484684.

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