Bis-tris methane

Bis-tris methane
Names
IUPAC name
2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol[1]
Other names
  • Bis-(2-hydroxy-ethyl)-amino-tris(hydroxymethyl)-methane
  • 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol
  • 2,2-Bis(hydroxymethyl)-2,2,2-nitrilotriethanol
Identifiers
3D model (JSmol)
2205275
ChEBI
ChemSpider
ECHA InfoCard 100.027.489
EC Number 230-237-7
4519
MeSH Bistris
RTECS number TY2900000
Properties
C8H19NO5
Molar mass 209.24 g·mol−1
Appearance White crystals
Odor Odourless
Melting point 102 to 103 °C (216 to 217 °F; 375 to 376 K)
209.2 g L−1 (at 20 °C)
Acidity (pKa) 6.46
Basicity (pKb) 7.54
UV-vis (λmax) 280 nm
Absorbance 0.15
Hazards
GHS pictograms
GHS signal word WARNING
H315, H319, H335
P261, P305+351+338
NFPA 704
Flammability code 0: Will not burn. E.g., waterHealth code 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g., chloroformReactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogenSpecial hazards (white): no codeNFPA 704 four-colored diamond
0
2
0
Related compounds
Related alkanols
Related compounds
 Diethylhydroxylamine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is ☑Y☒N ?)
Infobox references

Bis-tris methane, also known as BIS-TRIS or BTM, is a buffering agent used in biochemistry. Bis-tris methane is an organic tertiary amine with labile protons having a pKa of 6.46 at 25 °C. It is an effective buffer between the pH 5.8 and 7.2. Bis-tris methane binds strongly to Cu and Pb ions as well as, weakly, to Mg, Ca, Mn, Co, Ni, Zn and Cd.[2]

See also

References

  1. ↑ "Bistris - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 23 June 2005. Identification. Retrieved 9 April 2012.
  2. ↑ Ferreira, Carlos M. H.; Pinto, Isabel S. S.; Soares, Eduardo V.; Soares, Helena M. V. M. (2015). "(Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions – a review". RSC Advances. 5 (39): 30989–31003. doi:10.1039/c4ra15453c. ISSN 2046-2069.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.