Aaron Ciechanover
Aaron Ciechanover | |
---|---|
Prof. Ciechanover Speaking at the Technion, Israel, February 2018. | |
Born |
Haifa, British Mandate of Palestine (now Israel) | October 1, 1947
Nationality | Israeli |
Known for | Ubiquitin-mediated protein degradation |
Spouse(s) | Menucha Ciechanover |
Awards | Nobel Prize in Chemistry (2004) |
Scientific career | |
Fields | Biology |
Aaron Ciechanover (/ɑːhəˈroʊn
Biography
Ciechanover was born in Haifa, a year before the establishment of Israel. He is the son of Bluma (Lubashevsky), a teacher of English, and Yitzhak Ciechanover, an office worker.[1] His family were Jewish immigrants from Poland before World War II.
He earned a master's degree in science in 1971 and graduated from Hadassah Medical School in Jerusalem in 1974. On a visit to New York in 1977, Ciechanover spent two hours in a meeting with Rabbi Menachem M. Schneerson who discussed the nature of his research with him. He received his doctorate in biochemistry in 1981 from the Technion – Israel Institute of Technology in Haifa before conducting postdoctoral research in the laboratory of Harvey Lodish at the Whitehead Institute at MIT from 1981-1984. He is currently a Technion Distinguished Research Professor in the Ruth and Bruce Rappaport Faculty of Medicine and Research Institute at the Technion.
Ciechanover is a member of the Israel Academy of Sciences and Humanities, the Pontifical Academy of Sciences, and is a foreign associate of the United States National Academy of Sciences.
As one of Israel's first Nobel Laureates in Science, he is honored in playing a central role in the history of Israel and in the history of the Technion – Israel Institute of Technology.
Ciechanover is an atheist and does not believe in an afterlife, but strongly Jewish culturally.[2]
He lectured at the Pyongyang University of Science and Technology in North Korea in May 2016.
https://pust.co/index.php/2016/05/07/nobel-laureates-and-european-prince-visit-pust/
Publications
- Ciechanover, A., Hod, Y. and Hershko, A. (1978). A Heat-stable Polypeptide Component of an ATP-dependent Proteolytic System from Reticulocytes. Biochem. Biophys. Res. Commun. 81, 1100–1105.
- Ciechanover, A., Heller, H., Elias, S., Haas, A.L. and Hershko, A. (1980). ATP-dependent Conjugation of Reticulocyte Proteins with the Polypeptide Required for Protein Degradation. Proc. Natl. Acad. Sci. USA 77, 1365–1368.
- Hershko, A. and Ciechanover, A. (1982). Mechanisms of intracellular protein breakdown. Annu. Rev. Biochem. 51, 335–364.
Industry involvement
Ciechanover has served on the Scientific Advisory Boards of the following companies: Rosetta Genomics (Chairman), BioLineRx, Ltd, StemRad, Ltd, Allosterix Ltd, Proteologics, Inc, MultiGene Vascular Systems, Ltd, Protalix BioTherapeutics and BioTheryX, Inc.
Ciechanover is a member of the Advisory Board of Patient Innovation, a nonprofit, international, multilingual, free venue for patients and caregivers of any disease to share their innovations.
Awards
- In 2000, Ciechanover received the Albert Lasker Award for Basic Medical Research.
- In 2003, he was awarded the Israel Prize, for biology.[3][4]
- In 2004, he was awarded Nobel Prize in Chemistry for his discovery with Avram Hershko and Irwin Rose, of ubiquitin-mediated protein degradation.[5][6] The ubiquitin-proteasome pathway has a critical role in maintaining the homeostasis of cells and is believed to be involved in the development and progression of diseases such as: cancer, muscular and neurological diseases, immune and inflammatory responses.
- In 2006, he was awarded the Sir Hans Krebs Medal[7]
- In 2009, he was conferred an Honorary Doctorate in Science by the University of Cambodia[8]
See also
References
- ↑ http://encyclopedia.jrank.org/articles/pages/5635/Ciechanover-Aaron-1947.html
- ↑ J. (2013). 50 Renowned Academics Speaking About God (Part 3). Retrieved September 04, 2016, from https://www.youtube.com/watch?v=HHv__O8wvZI
- ↑ "Israel Prize Official Site (in Hebrew) – Recipient's C.V."
- ↑ "Israel Prize Official Site (in Hebrew) – Judges' Rationale for Grant to Recipient".
- ↑ Nobel citation
- ↑ Aaron Ciechanover and Avram Hershko 2004 Nobel in Chemistry Archived 2005-12-19 at the Wayback Machine. – A web article
- ↑ "Sir Hans Krebs Medal to Harald Stenmark". Oslo University Hospital. Retrieved 16 December 2014.
- ↑ "Welcome to The University of Cambodia (UC)". uc.edu.kh. Retrieved 2018-05-09.
External links
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