3-Hydroxypropionate bicycle

The 3-Hydroxypropionate bicycle, also known as the 3-Hydroxypropionate pathway, is a process that allows some bacteria to generate 3-Hydroxypropionate utilizing carbon dioxide. In this pathway CO2 is fixed (i.e. incorporated) by the action of two enzymes, acetyl-CoA carboxylase and propionyl-CoA carboxylase. These enzymes generate malonyl-CoA and (S)-methylmalonyl-CoA, respectively. Malonyl-CoA, in a series of reactions is further split into acetyl-CoA and glyoxylate. Glyoxylate is incorporated into beta-methylmalyl-coA which is then split, again through a series of reactions to release pyruvate as well as acetate, which is used to replenish the cycle. This pathway has been demonstrated in Chloroflexus, a nonsulfur photosynthetic bacterium, however other studies suggest that 3-hydroxypropionate bicycle is utilized by several chemotrophic archaea.[1][2]

See also

References

  1. ↑ Tabita, F. Robert (2009-12-15). "The hydroxypropionate pathway of CO2 fixation: Fait accompli". Proceedings of the National Academy of Sciences. 106 (50): 21015–21016. doi:10.1073/pnas.0912486107. ISSN 0027-8424. PMC 2795556. PMID 19996176.
  2. ↑ Hügler, Michael; Sievert, Stefan M. (2011). "Beyond the Calvin Cycle: Autotrophic Carbon Fixation in the Ocean". Annual Review of Marine Science. 3 (1): 261–289. doi:10.1146/annurev-marine-120709-142712. PMID 21329206.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.