< Radiation Oncology < Endometrium

Endometrial Cancer: GOG OPEN TRIALS
NumberTitle
GOG-0258Phase III Randomized Study of Adjuvant Chemoradiotherapy Comprising Cisplatin and Tumor Volume-Directed Radiotherapy Followed by Carboplatin and Paclitaxel Versus Carboplatin and Paclitaxel Alone in Patients With Stage III or IVA Endometrial Carcinoma
GOG-0249Phase III Randomized Study of Pelvic Radiotherapy Versus Vaginal Cuff Brachytherapy, Paclitaxel, and Carboplatin in Patients With High-Risk Stage I or II Endometrial Carcinoma
GOG-0247Study of Patient, Physician, and Nurse Factors Associated With Entry Onto Clinical Trials and Completion of Treatment in Patients With Primary or Recurrent Invasive Carcinoma of the Uterine Corpus or Uterine Cervix
GOG-0244Prospective Study of the Incidence, Risk Factors, and Impact of Lymphedema After Radical Surgery in Patients With Stage I-II Endometrial (Uterine) Cancer, Stage IA-IIA Cervical Cancer, or Stage I-IV Vulvar Cancer
GOG-0238Phase II Randomized Study of Pelvic Radiotherapy With Versus Without Cisplatin in Patients With Recurrent Endometrial Cancer
GOG-0233Phase I/II Study of the Utility of Preoperative Fludeoxyglucose F 18 Positron Emission Tomography/CT Scanning and Ferumoxtran-10 MRI Scanning Prior to Primary Chemoradiotherapy in Detecting Retroperitoneal Lymph Node Metastasis in Patients With Locoregionally Advanced Carcinoma of the Cervix or High-Risk Endometrial Carcinoma
GOG-0229HPhase II Study of MEK inhibitor AZD6244 in Patients With Recurrent or Persistent Endometrial Carcinoma
GOG-0210Study to Collect Clinical Specimens For Molecular Staging of Endometrial Carcinoma
GOG-0136Research Study of Collection of Gynecological Tumor Specimens
GOG-0086PPhase II Randomized Study of Paclitaxel, Carboplatin, and Bevacizumab Versus Paclitaxel, Carboplatin, and Temsirolimus Versus Ixabepilone, Carboplatin, and Bevacizumab in Patients With Stage III-IV or Recurrent Endometrial Cancer
GOG-9920Phase I Study of Doxorubicin Hydrochloride in Combination With Intraperitoneal (IP) Paclitaxel and Intravenous or IP Cisplatin in Patients With Endometrial Cancer At High Risk for Peritoneal Failure


Endometrial Cancer: GOG CLOSED TRIALS INVOLVING RADIATION
NumberTitlePublication
GOG-0184Phase III Randomized Adjuvant Study of Tumor Volume-Directed Pelvic Radiotherapy With or Without Paraaortic Radiotherapy Followed By Cisplatin and Doxorubicin With or Without Paclitaxel in Patients With Stage III Endometrial CarcinomaPMID 19108877
GOG-0156Phase III Randomized Study of Adjuvant Pelvic Irradiation vs DOX/CDDP for Stage IB/IC/IIA/IIB Endometrial CarcinomaTerminated
GOG-9908Phase I Study of Doxorubicin and Cisplatin Followed By Whole Abdominal Radiotherapy in Patients With Stage III or IV Endometrial CancerPMID 19135232
GOG-9907Phase I Study of Paclitaxel and Cisplatin With Radiotherapy in Patients With Stage III or IV Endometrial CancerPMID 18962846
GOG-9905Phase III Randomized Study of Adjuvant Radiotherapy With or Without Cisplatin and Paclitaxel After Total Abdominal Hysterectomy and Bilateral Salpingo-oophorectomy in Patients With Stage I or II Endometrial Cancer (also RTOG 9905)Terminated
GOG-9403Phase I Dose-Seeking Study of TAX Administered During Pelvic Irradiation for Advanced or Recurrent Cancer of the Cervix, Vagina, Endometrium, or Bladder 
GOG-9301Phase I Study of Weekly CDDP and Whole-Abdominal Radiotherapy Followed by DOX/CDDP in Patients with Stage III/IV Endometrial CarcinomaPMID 15385116
GOG-147Companion Protocol to Evaluate the Quality of Life in Patients with Advanced Endometrial Cancer Simultaneously Enrolled on GOG-122 
GOG-122Phase III Randomized Trial of Whole-Abdominal Irradiation vs DOX/CDDP in Patients Who Have Undergone Maximum Debulking of Advanced Endometrial CarcinomaPMID 16330675
GOG-99Phase III Randomized Evaluation of Adjuvant Postoperative Pelvic Radiotherapy vs No Adjuvant Therapy for Surgical Stage I and Occult Stage II Intermediate-Risk Endometrial CarcinomaPMID 14984936
GOG-94Phase II Study of Whole-Abdominal Radiotherapy in Patients with Papillary Serous Carcinoma and Clear Cell Carcinoma of the Endometrium or with Maximally Debulked Advanced Endometrial CarcinomaPMID 16213007
GOG-18Multimodality Therapy with Surgery and Radiotherapy for Stage II Adenocarcinoma and Adeno-Acanthoma of the EndometriumTerminated
GOG-17Radiotherapy plus Endocrine Therapy with Progestin for Stage III and Stage IV Adenocarcinoma of the EndometriumTerminated
GOG-16Preoperative vs Postoperative Radiotherapy Adjunctive to Surgery for Stage I Adenocarcinoma of the EndometriumTerminated


Endometrial Cancer: GOG CLOSED TRIALS
NumberTitlePublication
GOG-0248Phase II Randomized Study of Temsirolimus With or Without Hormonal Therapy Comprising Megestrol Acetate and Tamoxifen Citrate in Patients With Advanced, Persistent, or Recurrent Endometrial Carcinoma 
GOG-0229IPhase II Study of Brivanib Alaninate in Patients With Recurrent or Persistent Endometrial Carcinoma 
GOG-0229GPhase II Study of Bevacizumab and Temsirolimus in Patients With Recurrent or Persistent Endometrial Carcinoma 
GOG-0229FPhase II Study of VEGF Trap in Patients With Recurrent or Persistent Endometrial Carcinoma 
GOG-0229EPhase II Study of Bevacizumab in Patients With Recurrent or Persistent Endometrial Cancer 
GOG-0229DPhase II Study of Lapatinib in Patients With Recurrent or Persistent Endometrial Carcinoma 
GOG-0229CPhase II Study of Gefitinib in Patients With Persistent or Recurrent Endometrial Carcinoma 
GOG-0229BPhase II Study of Thalidomide in Patients With Recurrent or Persistent Endometrial CancerPMID 17306350
GOG-0224Phase II Randomized Study of Megestrol Acetate in Patients With Endometrial Intraepithelial Neoplasia or Atypical Endometrial Hyperplasia 
GOG-0211Phase II Pilot Study of Medroxyprogesterone in Patients With Endometrioid Adenocarcinoma of the Uterine Corpus 
GOG-0209Phase III Randomized Study of Doxorubicin, Cisplatin, Paclitaxel, and Filgrastim (G-CSF) Versus Carboplatin and Paclitaxel in Patients With Stage III or IV or Recurrent Endometrial Cancer 
GOG-0189Phase III Randomized Study of Doxorubicin, Cisplatin, Paclitaxel, and Filgrastim (G-CSF) Versus Tamoxifen and Megestrol in Patients With Stage III or IV or Recurrent Endometrial Cancer 
GOG-0188Phase II Study of Fulvestrant in Patients With Newly Recurrent, Persistent, or Metastatic Endometrial Cancer 
GOG-0184Phase III Randomized Adjuvant Study of Tumor Volume-Directed Pelvic Radiotherapy With or Without Paraaortic Radiotherapy Followed By Cisplatin and Doxorubicin With or Without Paclitaxel in Patients With Stage III Endometrial Carcinoma 
GOG-0181BPhase II Study of Trastuzumab (Herceptin®) in Patients With Advanced, Recurrent, or Persistent Endometrial AdenocarcinomaPMID 1984088
GOG-0177Phase III Randomized Study of Doxorubicin/Cisplatin With or Without Paclitaxel and Filgrastim (G-CSF) Support in Patients with Stage III, Stage IV, or Recurrent Endometrial Cancer 
GOG-0163Phase III Randomized Study of Doxorubicin/Cisplatin vs Doxorubicin/Paclitaxel/G-CSF for Primary Stage III/IV or Recurrent Endometrial Carcinoma 
GOG-0156Phase III Randomized Study of Adjuvant Pelvic Irradiation vs DOX/CDDP for Stage IB/IC/IIA/IIB Endometrial CarcinomaTerminated
GOG-0137APhase III Randomized Study of Estrogen Replacement Therapy Versus Placebo in Women With Stage I or II Endometrial Adenocarcinoma 
GOG-0129Q]Phase II Study of Gemcitabine Hydrochloride in Patients With Recurrent or Persistent Endometrial Adenocarcinoma 
GOG-0129PPhase II Study of Ixabepilone in Patients With Recurrent or Persistent Endometrial AdenocarcinomaPMID 19451430
GOG-0129OPhase II Study of Pemetrexed Disodium in Patients With Persistent or Recurrent Endometrial AdenocarcinomaPMID 19804902
GOG-0129NPhase II Study of Docetaxel in Patients With Recurrent or Persistent Endometrial CarcinomaPMID 18675446
GOG-0129MPhase II Study of Flavopiridol in Patients With Recurrent or Persistent Endometrial CarcinomaPMID 15978659
GOG-0129KPhase II Study of Oxaliplatin in Patients With Persistent or Recurrent Endometrial CarcinomaPMID 16712905
GOG-0087JPhase II Study of Doxorubicin HCl Liposome in Patients With Recurrent or Advanced Uterine SarcomaPMID 15721421
GOG-0086MPhase II Study of Doxorubicin HCl Liposome in Patients With Advanced or Recurrent Endometrial CancerPMID 15975638
GOG-0026AMaster Protocol Template for Individual Phase II Studies of New Drug Therapies in Patients With Metastatic or Recurrent Gynecologic Malignancies 
GOG-9908Phase I Study of Doxorubicin and Cisplatin Followed By Whole Abdominal Radiotherapy in Patients With Stage III or IV Endometrial CancerPMID 19135232
GOG-9907Phase I Study of Paclitaxel and Cisplatin With Radiotherapy in Patients With Stage III or IV Endometrial CancerPMID 18962846
GOG-9905Phase III Randomized Study of Adjuvant Radiotherapy With or Without Cisplatin and Paclitaxel After Total Abdominal Hysterectomy and Bilateral Salpingo-oophorectomy in Patients With Stage I or II Endometrial Cancer (also RTOG 9905)Terminated
GOG-9902Quality of Life of Gynecologic Cancer Survivors 
GOG-9805Phase II Study of Amifostine for Protection Against Cisplatin and Paclitaxel Induced Neurotoxicity in Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial CancerPMID 14615449
GOG-9405Phase I Study of Paclitaxel Combined with Fixed Doses of CDDP/DOX for Advanced Gynecologic Malignancies and Recurrent Bladder Cancer with or without Pelvic IrradiationPMID 11181665
GOG-9403Phase I Dose-Seeking Study of TAX Administered During Pelvic Irradiation for Advanced or Recurrent Cancer of the Cervix, Vagina, Endometrium, or Bladder 
GOG-9301Phase I Study of Weekly CDDP and Whole-Abdominal Radiotherapy Followed by DOX/CDDP in Patients with Stage III/IV Endometrial CarcinomaPMID 15385116
GOG-9206Phase II Study of Laparoscopic-Assisted Vaginal Hysterectomy/Bilateral Salpingo-Oophorectomy, Intraperitoneal Staging, and Pelvic and Aortic Lymph Node Sampling in Patients with Presumed Stage I/IIA Adenocarcinoma of the EndometriumPMID 15086735
GOG-9102The Effect of Alopecia on the Cancer Patient's Body Image and the Role of Audiovisual Information on Improving Body Image 
GOG-9101Phase I Study of Intraperitoneal TAX in Patients with Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cavity CarcinomaPMID 8523061
GOG-9001Phase I Limited-Access Study of Weekly Cisplatin and Whole-Abdominal Irradiation in Patients with Stage III/IV Endometrial CarcinomaPMID 8946862
GOG-8909Phase I Study of CDDP plus Cyclosporine in Patients with Refractory Gynecologic Cancer 
GOG-8808Phase I Study of Intraperitoneal Taxol in Patients with Recurrent and/or Persistent Gynecologic CarcinomaPMID 7912515
GOG-7892Phase II Hormone Therapy with Tamoxifen for Advanced or Recurrent Endometrial AdenocarcinomaTerminated
GOG-180Phase II Study of Danazol in Patients with Advanced or Recurrent Endometrial CancerPMID 12798713
GOG-168Phase II Study of Anastrozole (Arimidex) in Advanced, Recurrent or Persistent Endometrial CancerPMID 10926805
GOG-167Prospective Study of Immediate Hysterectomy and Phase II Randomized Study of Medroxyprogesterone Acetate (Provera) Versus Medroxyprogesterone Acetate Suspension (Depo-Provera) Prior to Hysterectomy in Patients With Atypical Endometrial HyperplasiaPMID 16400639
GOG-166Phase II Study of High-Dose Intravenous Progesterone and Doxorubicin for Progressive Endometrial Carcinoma Resistant to Ongoing Doxorubicin Alone 
GOG-159Phase II Study of ZDX in Advanced, Recurrent, or Persistent Endometrial Cancer 
GOG-153Phase II Study of Alternating Courses of Megestrol and Tamoxifen for Recurrent or Persistent Endometrial AdenocarcinomaPMID 14751131
GOG-147Companion Protocol to Evaluate the Quality of Life in Patients with Advanced Endometrial Cancer Simultaneously Enrolled on GOG-122 
GOG-139Phase III Randomized Study of DOX/CDDP Administered on Standard vs Circadian-Timed Schedules in Patients with Primary Stage III/IV/Recurrent Endometrial CarcinomaPMID 14551299
GOG-129LPhase II Study of 6-Hydroxymethylacylfulvene (Irofulven) in Patients With Persistent or Recurrent, Refractory Endometrial CarcinomaPMID 15122083
GOG-129JPhase II Study of Topotecan in Patients With Persistent, Recurrent, or Refractory Endometrial CarcinomaPMID 12468321
GOG-129IPhase II Study of Pyrazoloacridine (PZA) in Patients with Recurrent or Refractory Endometrial CarcinomaPMID 11812081
GOG-129HPhase II Study of the Effects of DOXIL in the Treatment of Recurrent or Persistent Endometrial CarcinomaPMID 11981008
GOG-129EPhase II Study of Dactinomycin for Recurrent or Persistent Endometrial CarcinomaPMID 10600310
GOG-129CPhase II Study of TAX for Recurrent or Persistent Endometrial CancerPMID 12648575
GOG-129BPhase II Study of Prolonged Oral VP-16 in Patients with Recurrent or Advanced Endometrial Cancer 
GOG-122Phase III Randomized Trial of Whole-Abdominal Irradiation vs DOX/CDDP in Patients Who Have Undergone Maximum Debulking of Advanced Endometrial CarcinomaPMID 16330675
GOG-121Phase II Trial of High-Dose MEG in Patients with Advanced or Recurrent Endometrial Carcinoma 
GOG-119Phase II Study of Tamoxifen plus Medroxyprogesterone for Advanced, Recurrent, or Metastatic Endometrial CarcinomaPMID 14751130
GOG-107Phase III Randomized Study Comparing ADR vs ADR/CACP in Patients with Recurrent Primary Stage III/IV Endometrial CarcinomaPMID 15459211
GOG-99Phase III Randomized Evaluation of Adjuvant Postoperative Pelvic Radiotherapy vs No Adjuvant Therapy for Surgical Stage I and Occult Stage II Intermediate-Risk Endometrial CarcinomaPMID 14984936
GOG-96Phase II Circadian-Timed Combination Chemotherapy with ADR/CDDP in Patients with Advanced Primary Endometrial CarcinomaPMID 8256764
GOG-94Phase II Study of Whole-Abdominal Radiotherapy in Patients with Papillary Serous Carcinoma and Clear Cell Carcinoma of the Endometrium or with Maximally Debulked Advanced Endometrial CarcinomaPMID 16213007
GOG-860Phase II Master Protocol for Chemotherapy in Patients with Advanced or Recurrent Carcinoma of the Endometrium --- TAX/G-CSF 
GOG-86JPhase II Master Protocol for Treatment of Patients with Advanced or Recurrent Carcinoma of the Endometrium --- Tumor Necrosis Factor 
GOG-86IPhase II Study of IFF/Mesna for Advanced or Recurrent Carcinoma of the Endometrium 
GOG-86EPhase II Master Protocol for Chemotherapy in Patients with Advanced or Recurrent Carcinoma of the Endometrium --- VincristinePMID 8424397
GOG-86DPhase II Master Protocol for Chemotherapy in Patients with Advanced or Recurrent Carcinoma of the Endometrium --- MTXPMID 2407104
GOG-86Phase II Master Protocol for Advanced or Recurrent Carcinoma of the Endometrium: Phase I/II Study of HexamethylmelaminePMID 3141250
GOG-083Phase II Clinico-Pathological Study of Adjuvant Chemotherapy with L-PAM in Patients with Simultaneous Endometrial and Ovarian Carcinoma 
GOG-81FMaster Protocol for Hormonal Treatment of Advanced or Recurrent Endometrial Carcinoma --- Phase II Tamoxifen for Disease Responsive to ProgestinsPMID 11208827
GOG-81Phase III Randomized Study of Low-Dose vs High-Dose Medroxyprogesterone Acetate (Provera) in Patients with Advanced, Persistent, or Recurrent Endometrial CarcinomaPMID 11208827
GOG-62Data Collection Form for Extravasation Injury with Doxorubicin 
GOG-48Phase III Provera (MPA) vs ADR vs ADR/CTX for Stage III/IV or Recurrent Endometrial CancerPMID 8021731
GOG-28Phase III L-PAM/5-FU/MEG Chemotherapy vs ADR/CTX/5-FU/MEG for Primary Stage III or IV Recurrent or Residual Endometrial CancerPMID 6371627
GOG-34Phase III Randomized Trial of Surgery plus Radiotherapy Followed by Chemotherapy with ADR vs Surgery plus Radiotherapy Alone in Patients with High-Risk Stage I/High-Risk Occult Stage II Endometrial Carcinoma, Including Those with Adnexal MetastasesPMID 2298404
GOG-30Phase II Chemotherapy with Adriamycin for Endometrial Adenocarcinoma 
GOG-26MMPhase II Master Protocol for Advanced, Recurrent Gynecologic Malignancies: EDAMPMID 7900709
GOG-26KKPhase II Master Protocol for Advanced, Recurrent Endometrial Carcinoma: MerbaronePMID 8554040
GOG-26HHPhase II Master Protocol for Advanced, Recurrent Pelvic Gynecologic Malignancies: Fluorouracil/Leucovorin 
GOG-26GGPhase II Master Protocol for Advanced, Recurrent Pelvic Gynecologic Malignancies: FazarabinePMID 7534978
GOG-26YPhase II Master Protocol for Advanced, Recurrent Gynecologic Malignancies: VinblastinePMID 2239800
GOG-26WPhase II Master Protocol for Advanced, Recurrent Gynecologic Malignancies: EchinomycinPMID 2198794
GOG-26VPhase II Master Protocol for Advanced, Recurrent Gynecologic Malignancies: N-MethylformamidePMID 2384305
GOG-26TPhase II Master Protocol Chemotherapy with 4'-Deoxydoxorubicin for Advanced, Recurrent Pelvic MalignanciesPMID 2557300
GOG-26PPhase II Master Protocol for Advanced, Recurrent Pelvic Malignancies: AT-125PMID 3700040
GOG-26MPhase II Chemotherapy with PALA for Advanced Recurrent Pelvic MalignanciesPMID 6731346
GOG-26KPhase II Chemotherapy with Chlorozotocin for Advanced, Recurrent and Metastatic Pelvic Malignancies in Progression 
GOG-26JPhase II Chemotherapy with YOSHI-864 for Advanced, Recurrent Pelvic MalignanciesPMID 6288239
GOG-26HPhase II Chemotherapy with Maytansine for Advanced Recurrent Pelvic MalignanciesPMID 6869315
GOG-26IPhase II Chemotherapy with AMSA for Advanced, Recurrent Pelvic Malignancies (Cervix)PMID 6687445
GOG-26GPhase II Master Protocol for Advanced, Recurrent Pelvic Malignancies: ICRF-159PMID 3953488
GOG-26FPhase II Chemotherapy with Baker's Antifol for Advanced Recurrent Pelvic MalignanciesPMID 6236163
GOG-26EPhase II Master Protocol for Advanced, Recurrent Gynecologic Malignancies: DianhydrogalactitolPMID 6511240
GOG-26DPhase II Master Protocol for Advanced, Recurrent Gynecologic Malignancies: VP-16PMID 6509456
GOG-26BPhase II Chemotherapy with Piperazinedione for Advanced Gynecologic Malignancies in WomenPMID 3754086
GOG-23Chemotherapy with ADR/VCR/CTX for Carcinoma of the Cervix and for Adenocarcinoma of the Endometrium 
GOG-18Multimodality Therapy with Surgery and Radiotherapy for Stage II Adenocarcinoma and Adeno-Acanthoma of the EndometriumTerminated
GOG-17Radiotherapy plus Endocrine Therapy with Progestin for Stage III and Stage IV Adenocarcinoma of the EndometriumTerminated
GOG-16Preoperative vs Postoperative Radiotherapy Adjunctive to Surgery for Stage I Adenocarcinoma of the EndometriumTerminated
GOG-15Modified Phase II-III Chemotherapy with CCNU or MeCCNU for Advanced Gynecologic CancersPMID 350400
GOG-P12Relation of Progestin Receptor Concentration to Efficacy of Progestin Therapy for Endometrial Adenocarcinoma - Pilot Study 
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