< Obstetrics and Gynecology

Epidemiology

Etiology

Pathophysiology

  • Factors released from the placenta (i.e. human placental lactogen, growth hormone, progesterone, and glucocorticoids) may aggravate maternal insulin resistance.
  • Increased insulin requirements during pregnancy may reveal a maternal incapacity to produce insulin from her pancreatic beta-cells.
  • Preexisting diabetes in the mother may worsen any already-present complications of diabetes.

Clinical Presentation

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